Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 12 studies | 24% ± 9% | |
fibroblast | 6 studies | 20% ± 5% | |
GABAergic neuron | 6 studies | 37% ± 18% | |
oligodendrocyte | 6 studies | 26% ± 7% | |
glutamatergic neuron | 5 studies | 48% ± 23% | |
adipocyte | 5 studies | 20% ± 3% | |
endothelial cell of lymphatic vessel | 5 studies | 22% ± 6% | |
astrocyte | 5 studies | 34% ± 10% | |
macrophage | 5 studies | 23% ± 4% | |
microglial cell | 4 studies | 23% ± 4% | |
epithelial cell | 4 studies | 31% ± 10% | |
oligodendrocyte precursor cell | 4 studies | 32% ± 9% | |
smooth muscle cell | 4 studies | 17% ± 0% | |
interneuron | 4 studies | 40% ± 22% | |
monocyte | 3 studies | 19% ± 2% | |
goblet cell | 3 studies | 28% ± 16% | |
transit amplifying cell | 3 studies | 29% ± 16% | |
neuron | 3 studies | 41% ± 12% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 1601.53 | 1445 / 1445 | 100% | 37.44 | 183 / 183 |
lung | 100% | 1571.20 | 578 / 578 | 100% | 22.99 | 1153 / 1155 |
ovary | 100% | 2005.11 | 180 / 180 | 100% | 23.42 | 429 / 430 |
intestine | 100% | 1677.74 | 966 / 966 | 99% | 19.84 | 521 / 527 |
breast | 100% | 1946.51 | 459 / 459 | 99% | 31.36 | 1104 / 1118 |
stomach | 100% | 1336.53 | 359 / 359 | 98% | 23.01 | 281 / 286 |
bladder | 100% | 1667.10 | 21 / 21 | 97% | 18.71 | 490 / 504 |
brain | 98% | 994.95 | 2592 / 2642 | 99% | 16.16 | 696 / 705 |
pancreas | 100% | 859.25 | 327 / 328 | 97% | 14.86 | 172 / 178 |
uterus | 100% | 2054.32 | 170 / 170 | 96% | 20.33 | 439 / 459 |
prostate | 100% | 1558.54 | 245 / 245 | 95% | 17.35 | 476 / 502 |
thymus | 100% | 1823.51 | 653 / 653 | 95% | 12.77 | 573 / 605 |
skin | 100% | 2178.98 | 1809 / 1809 | 94% | 20.44 | 443 / 472 |
kidney | 100% | 1246.10 | 89 / 89 | 92% | 13.04 | 828 / 901 |
adrenal gland | 100% | 1993.02 | 258 / 258 | 89% | 10.75 | 205 / 230 |
liver | 100% | 836.19 | 226 / 226 | 78% | 8.70 | 318 / 406 |
adipose | 100% | 2012.83 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 1807.42 | 1335 / 1335 | 0% | 0 | 0 / 0 |
spleen | 100% | 1722.48 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 5.65 | 1 / 1 |
muscle | 99% | 816.90 | 798 / 803 | 0% | 0 | 0 / 0 |
heart | 96% | 820.29 | 826 / 861 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 96% | 21.15 | 43 / 45 |
lymph node | 0% | 0 | 0 / 0 | 79% | 16.77 | 23 / 29 |
peripheral blood | 77% | 1079.45 | 712 / 929 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 76% | 12.34 | 61 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0051123 | Biological process | RNA polymerase II preinitiation complex assembly |
GO_0006282 | Biological process | regulation of DNA repair |
GO_0000086 | Biological process | G2/M transition of mitotic cell cycle |
GO_0060261 | Biological process | positive regulation of transcription initiation by RNA polymerase II |
GO_0014070 | Biological process | response to organic cyclic compound |
GO_0006367 | Biological process | transcription initiation at RNA polymerase II promoter |
GO_0042789 | Biological process | mRNA transcription by RNA polymerase II |
GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
GO_0033276 | Cellular component | transcription factor TFTC complex |
GO_0005669 | Cellular component | transcription factor TFIID complex |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0016251 | Molecular function | RNA polymerase II general transcription initiation factor activity |
GO_0005515 | Molecular function | protein binding |
GO_0003682 | Molecular function | chromatin binding |
GO_0000976 | Molecular function | transcription cis-regulatory region binding |
Gene name | TAF2 |
Protein name | Transcription initiation factor TFIID subunit 2 (150 kDa cofactor of initiator function) (RNA polymerase II TBP-associated factor subunit B) (TBP-associated factor 150 kDa) (Transcription initiation factor TFIID 150 kDa subunit) (TAF(II)150) (TAFII-150) (TAFII150) Transcription initiation factor TFIID subunit 2 (Transcription initiation factor TFIID 150 kDa subunit) TATA-box binding protein associated factor 2 Transcription initiation factor TFIID subunit 2 |
Synonyms | TAF2B CIF150 |
Description | FUNCTION: The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription . TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC) . The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13 . TAF2 forms a promoter DNA binding subcomplex of TFIID, together with TAF7 and TAF1 . . |
Accessions | ENST00000692916.1 ENST00000688645.1 A0A8I5KUQ2 A0A8I5KR26 A0A8I5KRI4 E5RI28 ENST00000688037.1 ENST00000685663.1 ENST00000685824.1 A0A8I5KU60 ENST00000686098.1 ENST00000685684.1 Q6P1X5 ENST00000378164.7 A0A8I5QJJ6 ENST00000685993.1 ENST00000689164.1 ENST00000529653.2 ENST00000691847.1 H0YB55 ENST00000685503.1 A0A8I5KNG3 ENST00000685876.1 A0A8I5KXS3 ENST00000690144.1 A0A8I5KV60 A0A8I5QJI9 ENST00000692518.1 ENST00000689919.1 ENST00000685202.1 ENST00000523904.2 ENST00000690922.1 A0A8I5QJD7 ENST00000521007.2 A0A8I5KSY6 ENST00000692707.1 A0A8I5KVC1 A0A8I5QJR0 ENST00000686879.1 H0YC37 A0A8I5KY57 ENST00000691880.1 ENST00000690031.1 ENST00000523098.1 A0A8I5KUD2 H0YEX2 ENST00000690808.1 ENST00000685235.1 A0A8I5KXP3 A0A8I5KPW0 |