CNTF report

I. Expression across cell types

Insufficient scRNA-seq data for expression of CNTF at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of CNTF at tissue level.

III. Associated gene sets

GO_0042531Biological processpositive regulation of tyrosine phosphorylation of STAT protein
GO_0046668Biological processregulation of retinal cell programmed cell death
GO_0048143Biological processastrocyte activation
GO_0060221Biological processretinal rod cell differentiation
GO_0007165Biological processsignal transduction
GO_0010628Biological processpositive regulation of gene expression
GO_0070120Biological processciliary neurotrophic factor-mediated signaling pathway
GO_0046533Biological processnegative regulation of photoreceptor cell differentiation
GO_0048666Biological processneuron development
GO_0048680Biological processpositive regulation of axon regeneration
GO_0048644Biological processmuscle organ morphogenesis
GO_0008284Biological processpositive regulation of cell population proliferation
GO_0043524Biological processnegative regulation of neuron apoptotic process
GO_0005615Cellular componentextracellular space
GO_0005576Cellular componentextracellular region
GO_0005737Cellular componentcytoplasm
GO_0030424Cellular componentaxon
GO_0044877Molecular functionprotein-containing complex binding
GO_0008083Molecular functiongrowth factor activity
GO_0005138Molecular functioninterleukin-6 receptor binding
GO_0005127Molecular functionciliary neurotrophic factor receptor binding
GO_0005515Molecular functionprotein binding
GO_0005125Molecular functioncytokine activity

IV. Literature review

[source]
Gene nameCNTF
Protein nameCiliary neurotrophic factor (CNTF)
Synonyms
DescriptionFUNCTION: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.

AccessionsENST00000361987.6
P26441