Name | Number of supported studies | Average coverage | |
---|---|---|---|
macrophage | 20 studies | 37% ± 19% | |
microglial cell | 20 studies | 66% ± 19% | |
oligodendrocyte | 15 studies | 54% ± 16% | |
epithelial cell of proximal tubule | 8 studies | 60% ± 23% | |
myeloid cell | 8 studies | 33% ± 13% | |
astrocyte | 7 studies | 41% ± 20% | |
kidney distal convoluted tubule epithelial cell | 7 studies | 56% ± 33% | |
endothelial cell | 7 studies | 43% ± 21% | |
kidney loop of Henle epithelial cell | 6 studies | 62% ± 20% | |
Mueller cell | 6 studies | 65% ± 25% | |
GABAergic neuron | 5 studies | 31% ± 8% | |
retina horizontal cell | 5 studies | 44% ± 19% | |
glial cell | 4 studies | 54% ± 20% | |
neuron | 3 studies | 26% ± 13% | |
abnormal cell | 3 studies | 44% ± 25% | |
pericyte | 3 studies | 35% ± 18% | |
epithelial cell | 3 studies | 52% ± 26% | |
basal cell | 3 studies | 27% ± 9% | |
pancreatic ductal cell | 3 studies | 66% ± 11% | |
conventional dendritic cell | 3 studies | 24% ± 6% | |
oligodendrocyte precursor cell | 3 studies | 29% ± 11% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
kidney | 100% | 205529.75 | 89 / 89 | 96% | 3717.55 | 861 / 901 |
brain | 91% | 18625.99 | 2398 / 2642 | 80% | 1993.53 | 566 / 705 |
pancreas | 95% | 11582.93 | 311 / 328 | 76% | 869.09 | 135 / 178 |
breast | 54% | 4223.86 | 246 / 459 | 45% | 336.57 | 506 / 1118 |
lung | 31% | 942.09 | 179 / 578 | 62% | 922.96 | 720 / 1155 |
ovary | 16% | 438.13 | 29 / 180 | 71% | 530.66 | 304 / 430 |
intestine | 60% | 1622.90 | 576 / 966 | 25% | 213.61 | 133 / 527 |
liver | 32% | 1244.21 | 72 / 226 | 44% | 1246.31 | 179 / 406 |
adipose | 65% | 6234.08 | 783 / 1204 | 0% | 0 | 0 / 0 |
skin | 2% | 45.49 | 42 / 1809 | 58% | 922.93 | 276 / 472 |
adrenal gland | 49% | 1367.13 | 126 / 258 | 7% | 54.63 | 17 / 230 |
bladder | 24% | 1362.57 | 5 / 21 | 27% | 290.93 | 134 / 504 |
esophagus | 17% | 337.02 | 248 / 1445 | 31% | 301.94 | 57 / 183 |
blood vessel | 46% | 5460.61 | 613 / 1335 | 0% | 0 | 0 / 0 |
uterus | 15% | 462.05 | 25 / 170 | 29% | 311.80 | 133 / 459 |
stomach | 22% | 425.85 | 78 / 359 | 21% | 157.77 | 59 / 286 |
eye | 0% | 0 | 0 / 0 | 36% | 400.56 | 29 / 80 |
heart | 30% | 1033.42 | 260 / 861 | 0% | 0 | 0 / 0 |
prostate | 29% | 747.78 | 70 / 245 | 1% | 3.76 | 6 / 502 |
thymus | 14% | 315.95 | 92 / 653 | 4% | 25.54 | 26 / 605 |
tonsil | 0% | 0 | 0 / 0 | 13% | 80.63 | 6 / 45 |
peripheral blood | 13% | 524.92 | 123 / 929 | 0% | 0 | 0 / 0 |
spleen | 7% | 193.58 | 18 / 241 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 7% | 55.26 | 2 / 29 |
muscle | 2% | 71.54 | 16 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_2000866 | Biological process | positive regulation of estradiol secretion |
GO_0036005 | Biological process | response to macrophage colony-stimulating factor |
GO_0046697 | Biological process | decidualization |
GO_0001649 | Biological process | osteoblast differentiation |
GO_0007165 | Biological process | signal transduction |
GO_0007155 | Biological process | cell adhesion |
GO_0071394 | Biological process | cellular response to testosterone stimulus |
GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
GO_0031214 | Biological process | biomineral tissue development |
GO_0048545 | Biological process | response to steroid hormone |
GO_0006710 | Biological process | androgen catabolic process |
GO_0045780 | Biological process | positive regulation of bone resorption |
GO_0033280 | Biological process | response to vitamin D |
GO_0007566 | Biological process | embryo implantation |
GO_0048685 | Biological process | negative regulation of collateral sprouting of intact axon in response to injury |
GO_0005615 | Cellular component | extracellular space |
GO_0005576 | Cellular component | extracellular region |
GO_0048471 | Cellular component | perinuclear region of cytoplasm |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005794 | Cellular component | Golgi apparatus |
GO_0005788 | Cellular component | endoplasmic reticulum lumen |
GO_0042995 | Cellular component | cell projection |
GO_0005178 | Molecular function | integrin binding |
GO_0005125 | Molecular function | cytokine activity |
GO_0036094 | Molecular function | small molecule binding |
GO_0050840 | Molecular function | extracellular matrix binding |
GO_0005515 | Molecular function | protein binding |
Gene name | SPP1 |
Protein name | Secreted phosphoprotein 1 variant 6 (cDNA FLJ54682, highly similar to Osteopontin) Osteopontin (Secreted phosphoprotein 1) Osteopontin (Bone sialoprotein 1) (Nephropontin) (Secreted phosphoprotein 1) (SPP-1) (Urinary stone protein) (Uropontin) Secreted phosphoprotein 1 |
Synonyms | OPN BNSP PSEC0156 opn |
Description | FUNCTION: Major non-collagenous bone protein that binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. .; FUNCTION: Acts as a cytokine involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10 and is essential in the pathway that leads to type I immunity. . |
Accessions | Q3LGB0 ENST00000360804.4 [P10451-3] ENST00000237623.11 [P10451-5] ENST00000614857.5 [P10451-1] P10451 ENST00000682655.1 A0A804HLB3 ENST00000395080.8 [P10451-1] ENST00000508233.6 B7Z351 |