I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| erythrocyte | 3 studies | 42% ± 12% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| erythrocyte | 3 studies | 42% ± 12% |
Insufficient scRNA-seq data for expression of C17orf99 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| peripheral blood | 97% | 106.82 | 904 / 929 | 0% | 0 | 0 / 0 |
| lung | 69% | 7.94 | 397 / 578 | 21% | 0.58 | 242 / 1155 |
| spleen | 84% | 21.70 | 203 / 241 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 79% | 12.05 | 23 / 29 |
| ovary | 69% | 11.94 | 124 / 180 | 9% | 0.18 | 39 / 430 |
| esophagus | 55% | 6.49 | 795 / 1445 | 17% | 0.33 | 31 / 183 |
| skin | 70% | 19.02 | 1275 / 1809 | 1% | 0.02 | 5 / 472 |
| prostate | 60% | 5.95 | 146 / 245 | 1% | 0.02 | 5 / 502 |
| uterus | 40% | 5.25 | 68 / 170 | 18% | 0.39 | 81 / 459 |
| breast | 52% | 4.48 | 237 / 459 | 0% | 0.01 | 5 / 1118 |
| bladder | 38% | 1.90 | 8 / 21 | 9% | 0.22 | 44 / 504 |
| intestine | 40% | 4.92 | 384 / 966 | 6% | 0.14 | 30 / 527 |
| adipose | 45% | 3.76 | 537 / 1204 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 33% | 1.01 | 15 / 45 |
| kidney | 29% | 3.22 | 26 / 89 | 1% | 0.07 | 12 / 901 |
| stomach | 16% | 1.00 | 56 / 359 | 5% | 0.09 | 14 / 286 |
| liver | 18% | 1.51 | 40 / 226 | 1% | 0.03 | 6 / 406 |
| thymus | 13% | 1.79 | 85 / 653 | 4% | 0.13 | 23 / 605 |
| pancreas | 12% | 0.76 | 38 / 328 | 5% | 0.12 | 9 / 178 |
| brain | 14% | 0.80 | 372 / 2642 | 1% | 0.02 | 5 / 705 |
| adrenal gland | 9% | 0.44 | 22 / 258 | 1% | 0.02 | 2 / 230 |
| heart | 6% | 0.31 | 52 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 6% | 0.40 | 80 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 3% | 0.16 | 26 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006955 | Biological process | immune response |
| GO_0002250 | Biological process | adaptive immune response |
| GO_2000558 | Biological process | positive regulation of immunoglobulin production in mucosal tissue |
| GO_0002313 | Biological process | mature B cell differentiation involved in immune response |
| GO_0007166 | Biological process | cell surface receptor signaling pathway |
| GO_0005615 | Cellular component | extracellular space |
| GO_0009897 | Cellular component | external side of plasma membrane |
| GO_0004888 | Molecular function | transmembrane signaling receptor activity |
| GO_0005125 | Molecular function | cytokine activity |
| Gene name | C17orf99 |
| Protein name | Protein IL-40 (Interleukin-40) (IL-40) Chromosome 17 open reading frame 99 |
| Synonyms | IL40 UNQ464/PRO809 |
| Description | FUNCTION: Probable B cell-associated cytokine that plays a role in the regulation of humoral immune responses. Involved in lymphocyte B cell development and immunoglobulin/IgA production. . |
| Accessions | Q6UX52 ENST00000340363.10 A0A0D9SGD8 ENST00000586029.1 ENST00000591995.1 K7ELL6 |
