Insufficient scRNA-seq data for expression of LEFTY2 at single-cell level.
Insufficient scRNA-seq data for expression of LEFTY2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 100% | 2793.23 | 180 / 180 | 36% | 2.17 | 156 / 430 |
uterus | 99% | 6718.11 | 168 / 170 | 36% | 7.70 | 167 / 459 |
prostate | 54% | 124.28 | 133 / 245 | 48% | 1.53 | 240 / 502 |
lung | 82% | 185.78 | 474 / 578 | 18% | 0.57 | 209 / 1155 |
blood vessel | 97% | 890.92 | 1301 / 1335 | 0% | 0 | 0 / 0 |
intestine | 44% | 78.40 | 422 / 966 | 20% | 1.24 | 106 / 527 |
brain | 3% | 3.25 | 74 / 2642 | 59% | 7.11 | 418 / 705 |
breast | 32% | 42.95 | 145 / 459 | 24% | 1.93 | 269 / 1118 |
heart | 54% | 78.95 | 465 / 861 | 0% | 0 | 0 / 0 |
bladder | 24% | 16.57 | 5 / 21 | 20% | 0.85 | 102 / 504 |
adrenal gland | 29% | 32.91 | 76 / 258 | 9% | 0.51 | 20 / 230 |
adipose | 36% | 61.64 | 432 / 1204 | 0% | 0 | 0 / 0 |
stomach | 14% | 14.51 | 50 / 359 | 20% | 0.84 | 56 / 286 |
spleen | 31% | 34.54 | 74 / 241 | 0% | 0 | 0 / 0 |
kidney | 19% | 14.84 | 17 / 89 | 6% | 0.44 | 54 / 901 |
pancreas | 9% | 10.17 | 30 / 328 | 13% | 0.21 | 23 / 178 |
eye | 0% | 0 | 0 / 0 | 18% | 1.34 | 14 / 80 |
muscle | 12% | 27.01 | 100 / 803 | 0% | 0 | 0 / 0 |
skin | 9% | 8.79 | 170 / 1809 | 3% | 0.13 | 13 / 472 |
thymus | 2% | 1.66 | 12 / 653 | 8% | 0.37 | 51 / 605 |
esophagus | 5% | 4.55 | 69 / 1445 | 4% | 0.07 | 8 / 183 |
liver | 0% | 1.06 | 1 / 226 | 2% | 0.13 | 8 / 406 |
peripheral blood | 0% | 0.05 | 1 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007165 | Biological process | signal transduction |
GO_0009948 | Biological process | anterior/posterior axis specification |
GO_0005615 | Cellular component | extracellular space |
GO_0031093 | Cellular component | platelet alpha granule lumen |
GO_0005576 | Cellular component | extracellular region |
GO_0062023 | Cellular component | collagen-containing extracellular matrix |
GO_0005160 | Molecular function | transforming growth factor beta receptor binding |
GO_0005125 | Molecular function | cytokine activity |
GO_0008083 | Molecular function | growth factor activity |
Gene name | LEFTY2 |
Protein name | Left-right determination factor 2 (Endometrial bleeding-associated factor) (Left-right determination factor A) (Protein lefty-2) (Protein lefty-A) (Transforming growth factor beta-4) (TGF-beta-4) |
Synonyms | TGFB4 EBAF PSEC0024 LEFTA LEFTYA |
Description | FUNCTION: Required for left-right (L-R) asymmetry determination of organ systems in mammals. May play a role in endometrial bleeding. |
Accessions | ENST00000420304.6 [O00292-2] ENST00000366820.10 [O00292-1] O00292 |