IL31 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of IL31 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of IL31 at tissue level.

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0002376Biological processimmune system process
GO_0005615Cellular componentextracellular space
GO_0005576Cellular componentextracellular region
GO_0005126Molecular functioncytokine receptor binding
GO_0005515Molecular functionprotein binding
GO_0005125Molecular functioncytokine activity

IV. Literature review

[source]
Gene nameIL31
Protein nameInterleukin-31 (IL-31)
Synonyms
DescriptionFUNCTION: Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR . May function in skin immunity . Enhances myeloid progenitor cell survival in vitro (By similarity). Induces RETNLA and serum amyloid A protein expression in macrophages (By similarity). .

AccessionsENST00000377035.2
Q6EBC2