GDF9 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of GDF9 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	100%	96.38	2629 / 2642	93%	2.71	654 / 705
breast	96%	54.45	439 / 459	58%	9.61	646 / 1118
adrenal gland	99%	72.19	256 / 258	52%	0.99	119 / 230
ovary	91%	43.86	164 / 180	53%	1.11	229 / 430
prostate	99%	71.94	243 / 245	45%	0.82	226 / 502
thymus	100%	92.05	652 / 653	38%	0.63	227 / 605
kidney	100%	81.82	89 / 89	34%	0.61	310 / 901
skin	95%	76.99	1718 / 1809	23%	0.40	107 / 472
uterus	92%	37.07	157 / 170	21%	0.47	98 / 459
bladder	95%	64.19	20 / 21	15%	0.38	74 / 504
pancreas	99%	66.63	326 / 328	9%	0.24	16 / 178
esophagus	92%	36.56	1324 / 1445	12%	0.21	22 / 183
liver	91%	35.92	205 / 226	13%	0.18	51 / 406
stomach	98%	78.00	352 / 359	5%	0.12	14 / 286
lung	83%	33.69	479 / 578	18%	0.32	203 / 1155
intestine	95%	41.05	915 / 966	5%	0.14	24 / 527
spleen	99%	51.40	239 / 241	0%	0	0 / 0
blood vessel	93%	38.50	1246 / 1335	0%	0	0 / 0
muscle	91%	48.02	732 / 803	0%	0	0 / 0
adipose	89%	39.05	1067 / 1204	0%	0	0 / 0
heart	65%	17.96	556 / 861	0%	0	0 / 0
peripheral blood	33%	17.28	308 / 929	0%	0	0 / 0
lymph node	0%	0	0 / 0	14%	0.20	4 / 29
eye	0%	0	0 / 0	13%	0.17	10 / 80
tonsil	0%	0	0 / 0	7%	0.09	3 / 45
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0001555	Biological process	oocyte growth
GO_0008284	Biological process	positive regulation of cell population proliferation
GO_0007292	Biological process	female gamete generation
GO_0007179	Biological process	transforming growth factor beta receptor signaling pathway
GO_2000870	Biological process	regulation of progesterone secretion
GO_0030308	Biological process	negative regulation of cell growth
GO_0005615	Cellular component	extracellular space
GO_0005737	Cellular component	cytoplasm
GO_0005125	Molecular function	cytokine activity
GO_0008083	Molecular function	growth factor activity

Gene name	GDF9
Protein name	Growth/differentiation factor 9 (GDF-9) Growth/differentiation factor 9
Synonyms
Description	FUNCTION: Required for ovarian folliculogenesis. Promotes primordial follicle development. Stimulates granulosa cell proliferation. Promotes cell transition from G0/G1 to S and G2/M phases, through an increase of CCND1 and CCNE1 expression, and RB1 phosphorylation. It regulates STAR expression and cAMP-dependent progesterone release in granulosa and thecal cells. Attenuates the suppressive effects of activin A on STAR expression and progesterone production by increasing the expression of inhibin B. It suppresses FST and FSTL3 production in granulosa-lutein cells. .
Accessions	ENST00000687214.1 ENST00000378673.2 O60383 A0A8I5KUL2 ENST00000624495.4 B4DXG3 ENST00000296875.4 ENST00000464378.2 ENST00000621295.5 ENST00000624492.4 ENST00000687138.1

GDF9 report