Insufficient scRNA-seq data for expression of CER1 at single-cell level.
Insufficient scRNA-seq data for expression of CER1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| kidney | 92% | 17.08 | 82 / 89 | 0% | 0.01 | 3 / 901 |
| uterus | 79% | 9.45 | 135 / 170 | 2% | 0.04 | 10 / 459 |
| blood vessel | 78% | 8.01 | 1038 / 1335 | 0% | 0 | 0 / 0 |
| pancreas | 72% | 5.58 | 236 / 328 | 1% | 0.02 | 1 / 178 |
| brain | 62% | 8.89 | 1639 / 2642 | 8% | 0.26 | 53 / 705 |
| intestine | 64% | 6.82 | 619 / 966 | 2% | 0.32 | 12 / 527 |
| adipose | 56% | 3.43 | 673 / 1204 | 0% | 0 | 0 / 0 |
| adrenal gland | 54% | 2.77 | 139 / 258 | 0% | 0.01 | 1 / 230 |
| bladder | 52% | 1.86 | 11 / 21 | 1% | 0.02 | 4 / 504 |
| breast | 52% | 3.34 | 240 / 459 | 1% | 0.01 | 7 / 1118 |
| heart | 49% | 2.51 | 418 / 861 | 0% | 0 | 0 / 0 |
| lung | 39% | 1.76 | 226 / 578 | 2% | 0.09 | 23 / 1155 |
| skin | 30% | 1.21 | 536 / 1809 | 1% | 0.02 | 7 / 472 |
| ovary | 29% | 0.97 | 52 / 180 | 1% | 0.01 | 3 / 430 |
| prostate | 27% | 0.98 | 65 / 245 | 1% | 0.02 | 4 / 502 |
| esophagus | 24% | 1.00 | 351 / 1445 | 2% | 0.08 | 4 / 183 |
| stomach | 23% | 0.85 | 84 / 359 | 2% | 0.71 | 7 / 286 |
| thymus | 24% | 0.89 | 154 / 653 | 0% | 0.01 | 2 / 605 |
| liver | 17% | 0.50 | 38 / 226 | 2% | 0.35 | 7 / 406 |
| muscle | 17% | 0.46 | 140 / 803 | 0% | 0 | 0 / 0 |
| spleen | 16% | 0.53 | 38 / 241 | 0% | 0 | 0 / 0 |
| peripheral blood | 2% | 0.05 | 18 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0035582 | Biological process | sequestering of BMP in extracellular matrix |
| GO_0008285 | Biological process | negative regulation of cell population proliferation |
| GO_0001657 | Biological process | ureteric bud development |
| GO_0009948 | Biological process | anterior/posterior axis specification |
| GO_0071276 | Biological process | cellular response to cadmium ion |
| GO_0003419 | Biological process | growth plate cartilage chondrocyte proliferation |
| GO_0061371 | Biological process | determination of heart left/right asymmetry |
| GO_0030514 | Biological process | negative regulation of BMP signaling pathway |
| GO_0007369 | Biological process | gastrulation |
| GO_0032926 | Biological process | negative regulation of activin receptor signaling pathway |
| GO_0023019 | Biological process | signal transduction involved in regulation of gene expression |
| GO_0030178 | Biological process | negative regulation of Wnt signaling pathway |
| GO_2000381 | Biological process | negative regulation of mesoderm development |
| GO_0042074 | Biological process | cell migration involved in gastrulation |
| GO_0030282 | Biological process | bone mineralization |
| GO_0009952 | Biological process | anterior/posterior pattern specification |
| GO_0007399 | Biological process | nervous system development |
| GO_0048263 | Biological process | determination of dorsal identity |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005576 | Cellular component | extracellular region |
| GO_0042803 | Molecular function | protein homodimerization activity |
| GO_0016015 | Molecular function | morphogen activity |
| GO_0036122 | Molecular function | BMP binding |
| GO_0005125 | Molecular function | cytokine activity |
| Gene name | CER1 |
| Protein name | Cerberus 1, cysteine knot superfamily, homolog (Xenopus laevis) Cerberus (Cerberus-related protein) (DAN domain family member 4) |
| Synonyms | DAND4 |
| Description | FUNCTION: Cytokine that may play a role in anterior neural induction and somite formation during embryogenesis in part through a BMP-inhibitory mechanism. Can regulate Nodal signaling during gastrulation as well as the formation and patterning of the primitive streak (By similarity). . |
| Accessions | ENST00000380911.4 O95813 Q3SY34 |