WNT6 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of WNT6 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of WNT6 at tissue level.

III. Associated gene sets

GO_0042475Biological processodontogenesis of dentin-containing tooth
GO_0071300Biological processcellular response to retinoic acid
GO_0001658Biological processbranching involved in ureteric bud morphogenesis
GO_0072079Biological processnephron tubule formation
GO_0061303Biological processcornea development in camera-type eye
GO_0010628Biological processpositive regulation of gene expression
GO_0070172Biological processpositive regulation of tooth mineralization
GO_0060070Biological processcanonical Wnt signaling pathway
GO_0030182Biological processneuron differentiation
GO_0045165Biological processcell fate commitment
GO_0045893Biological processpositive regulation of DNA-templated transcription
GO_0009798Biological processaxis specification
GO_0060684Biological processepithelial-mesenchymal cell signaling
GO_0005615Cellular componentextracellular space
GO_0005576Cellular componentextracellular region
GO_0005886Cellular componentplasma membrane
GO_0030666Cellular componentendocytic vesicle membrane
GO_0005796Cellular componentGolgi lumen
GO_0070062Cellular componentextracellular exosome
GO_0031012Cellular componentextracellular matrix
GO_0009986Cellular componentcell surface
GO_0005788Cellular componentendoplasmic reticulum lumen
GO_0005109Molecular functionfrizzled binding
GO_0005125Molecular functioncytokine activity

IV. Literature review

[source]
Gene nameWNT6
Protein nameProtein Wnt
Protein Wnt-6
Synonyms
DescriptionFUNCTION: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. Together with CAV1 may promote chemoresistance of gastric cancer cells to DNA-damaging anthracycline drugs through the activation of the canonical Wnt receptor signaling pathway. .

FUNCTION: Ligand for members of the frizzled family of seven transmembrane receptors. .

AccessionsQ9Y6F9
Q53S45
ENST00000233948.4