Insufficient scRNA-seq data for expression of WNT6 at single-cell level.
Insufficient scRNA-seq data for expression of WNT6 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 97% | 227.77 | 175 / 180 | 94% | 25.99 | 403 / 430 |
prostate | 96% | 261.44 | 236 / 245 | 55% | 1.82 | 278 / 502 |
uterus | 98% | 238.41 | 167 / 170 | 42% | 4.29 | 191 / 459 |
bladder | 90% | 150.14 | 19 / 21 | 46% | 4.38 | 230 / 504 |
esophagus | 87% | 237.63 | 1251 / 1445 | 40% | 3.32 | 74 / 183 |
breast | 90% | 297.04 | 412 / 459 | 36% | 3.49 | 399 / 1118 |
intestine | 93% | 400.60 | 900 / 966 | 27% | 1.10 | 143 / 527 |
spleen | 100% | 558.33 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 2.34 | 1 / 1 |
skin | 69% | 138.29 | 1246 / 1809 | 30% | 1.70 | 143 / 472 |
stomach | 68% | 176.87 | 244 / 359 | 30% | 1.55 | 87 / 286 |
lymph node | 0% | 0 | 0 / 0 | 97% | 8.03 | 28 / 29 |
adrenal gland | 21% | 36.55 | 55 / 258 | 74% | 10.62 | 171 / 230 |
adipose | 92% | 258.32 | 1105 / 1204 | 0% | 0 | 0 / 0 |
kidney | 60% | 65.06 | 53 / 89 | 29% | 0.88 | 262 / 901 |
heart | 85% | 128.13 | 728 / 861 | 0% | 0 | 0 / 0 |
brain | 43% | 166.70 | 1138 / 2642 | 38% | 1.10 | 269 / 705 |
thymus | 63% | 87.84 | 409 / 653 | 14% | 0.54 | 84 / 605 |
tonsil | 0% | 0 | 0 / 0 | 53% | 2.00 | 24 / 45 |
pancreas | 18% | 15.15 | 58 / 328 | 32% | 0.84 | 57 / 178 |
blood vessel | 39% | 63.72 | 522 / 1335 | 0% | 0 | 0 / 0 |
muscle | 35% | 39.30 | 282 / 803 | 0% | 0 | 0 / 0 |
lung | 12% | 11.05 | 71 / 578 | 22% | 1.50 | 256 / 1155 |
eye | 0% | 0 | 0 / 0 | 21% | 0.45 | 17 / 80 |
liver | 1% | 0.70 | 2 / 226 | 9% | 1.14 | 36 / 406 |
peripheral blood | 8% | 8.46 | 75 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0042475 | Biological process | odontogenesis of dentin-containing tooth |
GO_0071300 | Biological process | cellular response to retinoic acid |
GO_0001658 | Biological process | branching involved in ureteric bud morphogenesis |
GO_0072079 | Biological process | nephron tubule formation |
GO_0061303 | Biological process | cornea development in camera-type eye |
GO_0010628 | Biological process | positive regulation of gene expression |
GO_0070172 | Biological process | positive regulation of tooth mineralization |
GO_0060070 | Biological process | canonical Wnt signaling pathway |
GO_0030182 | Biological process | neuron differentiation |
GO_0045165 | Biological process | cell fate commitment |
GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
GO_0009798 | Biological process | axis specification |
GO_0060684 | Biological process | epithelial-mesenchymal cell signaling |
GO_0005615 | Cellular component | extracellular space |
GO_0005576 | Cellular component | extracellular region |
GO_0005886 | Cellular component | plasma membrane |
GO_0030666 | Cellular component | endocytic vesicle membrane |
GO_0005796 | Cellular component | Golgi lumen |
GO_0070062 | Cellular component | extracellular exosome |
GO_0031012 | Cellular component | extracellular matrix |
GO_0009986 | Cellular component | cell surface |
GO_0005788 | Cellular component | endoplasmic reticulum lumen |
GO_0005109 | Molecular function | frizzled binding |
GO_0005125 | Molecular function | cytokine activity |
Gene name | WNT6 |
Protein name | Protein Wnt Protein Wnt-6 |
Synonyms | |
Description | FUNCTION: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. Together with CAV1 may promote chemoresistance of gastric cancer cells to DNA-damaging anthracycline drugs through the activation of the canonical Wnt receptor signaling pathway. . FUNCTION: Ligand for members of the frizzled family of seven transmembrane receptors. . |
Accessions | Q9Y6F9 Q53S45 ENST00000233948.4 |