Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| neuron | 5 studies | 30% ± 17% | |
| hematopoietic precursor cell | 3 studies | 34% ± 7% | |
| common myeloid progenitor | 3 studies | 48% ± 19% | |
| hematopoietic stem cell | 3 studies | 48% ± 7% | |
| fibroblast | 3 studies | 19% ± 3% | |
| glutamatergic neuron | 3 studies | 22% ± 6% |
Insufficient scRNA-seq data for expression of C1QTNF4 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 99% | 3118.95 | 2605 / 2642 | 97% | 11.82 | 684 / 705 |
| ovary | 97% | 753.41 | 175 / 180 | 91% | 8.21 | 393 / 430 |
| uterus | 88% | 413.48 | 150 / 170 | 35% | 3.50 | 161 / 459 |
| prostate | 54% | 147.24 | 132 / 245 | 46% | 0.98 | 231 / 502 |
| breast | 39% | 106.62 | 181 / 459 | 28% | 0.76 | 309 / 1118 |
| intestine | 43% | 128.16 | 418 / 966 | 19% | 0.37 | 98 / 527 |
| adrenal gland | 10% | 25.25 | 27 / 258 | 50% | 3.27 | 116 / 230 |
| eye | 0% | 0 | 0 / 0 | 53% | 1.51 | 42 / 80 |
| tonsil | 0% | 0 | 0 / 0 | 51% | 2.55 | 23 / 45 |
| thymus | 17% | 42.61 | 113 / 653 | 27% | 1.63 | 164 / 605 |
| pancreas | 0% | 0 | 0 / 328 | 43% | 1.12 | 77 / 178 |
| stomach | 20% | 60.62 | 72 / 359 | 22% | 0.81 | 64 / 286 |
| skin | 13% | 30.41 | 228 / 1809 | 29% | 1.15 | 137 / 472 |
| esophagus | 18% | 48.24 | 262 / 1445 | 23% | 0.36 | 42 / 183 |
| bladder | 10% | 29.52 | 2 / 21 | 10% | 0.25 | 50 / 504 |
| adipose | 19% | 52.04 | 232 / 1204 | 0% | 0 | 0 / 0 |
| kidney | 7% | 14.63 | 6 / 89 | 9% | 0.19 | 85 / 901 |
| lung | 1% | 2.16 | 6 / 578 | 9% | 0.27 | 105 / 1155 |
| lymph node | 0% | 0 | 0 / 0 | 7% | 0.08 | 2 / 29 |
| blood vessel | 5% | 12.55 | 65 / 1335 | 0% | 0 | 0 / 0 |
| liver | 0% | 1.24 | 1 / 226 | 4% | 0.11 | 17 / 406 |
| spleen | 4% | 8.43 | 10 / 241 | 0% | 0 | 0 / 0 |
| muscle | 1% | 2.28 | 6 / 803 | 0% | 0 | 0 / 0 |
| heart | 0% | 1.05 | 4 / 861 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 929 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007165 | Biological process | signal transduction |
| GO_1901224 | Biological process | positive regulation of non-canonical NF-kappaB signal transduction |
| GO_0032755 | Biological process | positive regulation of interleukin-6 production |
| GO_0032760 | Biological process | positive regulation of tumor necrosis factor production |
| GO_0070105 | Biological process | positive regulation of interleukin-6-mediated signaling pathway |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005515 | Molecular function | protein binding |
| GO_0005125 | Molecular function | cytokine activity |
| GO_0003674 | Molecular function | molecular_function |
| Gene name | C1QTNF4 |
| Protein name | Complement C1q tumor necrosis factor-related protein 4 (C1q/TNF-related protein 4) C1q and TNF related 4 |
| Synonyms | CTRP4 |
| Description | FUNCTION: May be involved in the regulation of the inflammatory network. Its role as pro- or anti-inflammatory seems to be context dependent . Seems to have some role in regulating food intake and energy balance when administered in the brain. This effect is sustained over a two-day period, and it is accompanied by decreased expression of orexigenic neuropeptides in the hypothalamus 3 hours post-injection (By similarity). . |
| Accessions | ENST00000642567.2 E9PPZ5 ENST00000302514.4 Q9BXJ3 ENST00000530097.1 |
