TSLP report

I. Expression across cell types

Insufficient scRNA-seq data for expression of TSLP at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of TSLP at tissue level.

III. Associated gene sets

GO_0033005Biological processpositive regulation of mast cell activation
GO_0042531Biological processpositive regulation of tyrosine phosphorylation of STAT protein
GO_0032722Biological processpositive regulation of chemokine production
GO_1904894Biological processpositive regulation of receptor signaling pathway via STAT
GO_0032736Biological processpositive regulation of interleukin-13 production
GO_0001961Biological processpositive regulation of cytokine-mediated signaling pathway
GO_0032733Biological processpositive regulation of interleukin-10 production
GO_0038111Biological processinterleukin-7-mediated signaling pathway
GO_0032754Biological processpositive regulation of interleukin-5 production
GO_0071654Biological processpositive regulation of chemokine (C-C motif) ligand 1 production
GO_0043066Biological processnegative regulation of apoptotic process
GO_0008284Biological processpositive regulation of cell population proliferation
GO_0061844Biological processantimicrobial humoral immune response mediated by antimicrobial peptide
GO_0071657Biological processpositive regulation of granulocyte colony-stimulating factor production
GO_0050729Biological processpositive regulation of inflammatory response
GO_0007259Biological processcell surface receptor signaling pathway via JAK-STAT
GO_0032755Biological processpositive regulation of interleukin-6 production
GO_0005615Cellular componentextracellular space
GO_0005576Cellular componentextracellular region
GO_0005139Molecular functioninterleukin-7 receptor binding
GO_0005125Molecular functioncytokine activity

IV. Literature review

[source]
Gene nameTSLP
Protein nameThymic stromal lymphopoietin
Synonyms
DescriptionFUNCTION: [Isoform 1]: Cytokine that induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c(+) dendritic cells. Can induce allergic inflammation by directly activating mast cells. .; FUNCTION: [Isoform 2]: May act as an antimicrobial peptide in the oral cavity and on the skin. .

AccessionsQ969D9
ENST00000379706.4 [Q969D9-2]
ENST00000420978.6
ENST00000344895.4 [Q969D9-1]
A0A0C4DG43