GDF3 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of GDF3 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
kidney	75%	43.60	67 / 89	37%	1.14	329 / 901
adrenal gland	88%	17.69	228 / 258	14%	0.23	32 / 230
spleen	98%	51.26	237 / 241	0%	0	0 / 0
breast	78%	12.36	357 / 459	9%	0.14	105 / 1118
thymus	77%	12.31	500 / 653	7%	0.11	42 / 605
adipose	78%	16.83	941 / 1204	0%	0	0 / 0
uterus	68%	7.37	116 / 170	5%	0.15	23 / 459
bladder	62%	7.57	13 / 21	1%	0.02	6 / 504
ovary	42%	7.66	75 / 180	20%	1.35	88 / 430
esophagus	50%	5.75	723 / 1445	2%	0.05	3 / 183
heart	51%	4.87	435 / 861	0%	0	0 / 0
intestine	47%	4.16	456 / 966	2%	0.04	11 / 527
blood vessel	45%	7.70	606 / 1335	0%	0	0 / 0
prostate	42%	5.00	104 / 245	1%	0.07	6 / 502
lung	40%	3.46	229 / 578	2%	0.03	21 / 1155
skin	33%	3.11	593 / 1809	3%	0.12	15 / 472
stomach	30%	2.68	107 / 359	6%	0.10	16 / 286
muscle	22%	1.59	180 / 803	0%	0	0 / 0
pancreas	6%	0.36	21 / 328	9%	0.17	16 / 178
peripheral blood	9%	0.73	83 / 929	0%	0	0 / 0
liver	6%	0.23	13 / 226	0%	0.01	2 / 406
brain	4%	0.26	112 / 2642	2%	0.09	11 / 705
tonsil	0%	0	0 / 0	2%	0.02	1 / 45
eye	0%	0	0 / 0	1%	0.01	1 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0007498	Biological process	mesoderm development
GO_0001701	Biological process	in utero embryonic development
GO_0032525	Biological process	somite rostral/caudal axis specification
GO_0090009	Biological process	primitive streak formation
GO_0045662	Biological process	negative regulation of myoblast differentiation
GO_0007165	Biological process	signal transduction
GO_0045605	Biological process	negative regulation of epidermal cell differentiation
GO_0030514	Biological process	negative regulation of BMP signaling pathway
GO_0002021	Biological process	response to dietary excess
GO_0001654	Biological process	eye development
GO_0010453	Biological process	regulation of cell fate commitment
GO_0007492	Biological process	endoderm development
GO_0045600	Biological process	positive regulation of fat cell differentiation
GO_0001501	Biological process	skeletal system development
GO_0048859	Biological process	formation of anatomical boundary
GO_0030903	Biological process	notochord development
GO_0005615	Cellular component	extracellular space
GO_0005737	Cellular component	cytoplasm
GO_0019901	Molecular function	protein kinase binding
GO_0008083	Molecular function	growth factor activity
GO_0005125	Molecular function	cytokine activity

Gene name	GDF3
Protein name	Growth/differentiation factor 3 (GDF-3)
Synonyms	UNQ222/PRO248
Description	FUNCTION: Growth factor involved in early embryonic development and adipose-tissue homeostasis. During embryogenesis controls formation of anterior visceral endoderm and mesoderm and the establishment of anterior-posterior identity through a receptor complex comprising the receptor ACVR1B and the coreceptor CRIPTO (By similarity). Regulates adipose-tissue homeostasis and energy balance under nutrient overload in part by signaling through the receptor complex based on ACVR1C and CRIPTO/Cripto . .
Accessions	ENST00000329913.4 Q9NR23

GDF3 report