VSTM1 | OmnibusX

Name	Number of supported studies	Average coverage
classical monocyte	4 studies	24% ± 10%	Explore

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of VSTM1 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
spleen	97%	202.80	234 / 241	0%	0	0 / 0
lung	77%	53.90	443 / 578	14%	0.38	166 / 1155
peripheral blood	81%	1036.62	755 / 929	0%	0	0 / 0
brain	20%	5.86	524 / 2642	18%	0.62	130 / 705
ovary	1%	0.49	1 / 180	25%	1.36	107 / 430
pancreas	1%	0.28	4 / 328	22%	0.59	40 / 178
bladder	14%	5.52	3 / 21	8%	0.18	40 / 504
intestine	6%	1.76	62 / 966	9%	0.17	48 / 527
adrenal gland	10%	4.46	27 / 258	5%	0.13	11 / 230
stomach	4%	1.16	13 / 359	10%	0.18	28 / 286
adipose	12%	4.49	145 / 1204	0%	0	0 / 0
liver	10%	2.60	23 / 226	0%	0.01	2 / 406
kidney	3%	1.12	3 / 89	6%	0.16	58 / 901
uterus	3%	0.95	5 / 170	4%	0.13	19 / 459
lymph node	0%	0	0 / 0	7%	0.12	2 / 29
breast	2%	0.51	9 / 459	4%	0.06	44 / 1118
thymus	2%	0.45	15 / 653	3%	0.05	16 / 605
heart	3%	0.98	29 / 861	0%	0	0 / 0
esophagus	1%	0.30	16 / 1445	2%	0.06	4 / 183
prostate	2%	0.49	6 / 245	0%	0.01	2 / 502
blood vessel	3%	0.81	38 / 1335	0%	0	0 / 0
skin	0%	0.01	1 / 1809	3%	0.06	13 / 472
muscle	0%	0.02	1 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

IV. Literature review

[source]

Gene name	VSTM1
Protein name	V-set and transmembrane domain-containing protein 1 (Signal inhibitory receptor on leukocytes-1) (SIRL-1) V-set and transmembrane domain containing 1 (V-set and transmembrane domain-containing protein 1) V-set and transmembrane domain-containing protein 1 V-set and transmembrane domain containing 1 isoform e V-set and transmembrane domain containing 1 isoform d V-set and transmembrane domain containing 1
Synonyms	UNQ3033/PRO9835
Description	FUNCTION: [Isoform 2]: Behaves as a cytokine, promoting IL17A secretion by CD4+ T-cells, and differentiation and activation of IL17 producing helper T-cells (TH17).; FUNCTION: [Isoform 1]: Inhibitory immune receptor involved in the regulation of phagocytes.
Accessions	ENST00000622762.4 [Q6UX27-2] ENST00000614154.4 ENST00000613042.4 [Q6UX27-2] ENST00000619921.4 [Q6UX27-2] ENST00000447872.5 [Q6UX27-3] ENST00000614390.4 ENST00000617097.4 ENST00000645936.1 ENST00000610857.1 ENST00000613106.1 Q6UX27 ENST00000615235.4 [Q6UX27-2] ENST00000620314.4 ENST00000612639.4 ENST00000612942.4 ENST00000612864.4 [Q6UX27-3] ENST00000615508.4 [Q6UX27-2] ENST00000619907.4 ENST00000616582.4 D2DJS6 ENST00000617776.4 [Q6UX27-2] D2E0V1 ENST00000419106.5 ENST00000621018.1 ENST00000617862.4 [Q6UX27-1] ENST00000618109.4 ENST00000613399.4 ENST00000620474.4 [Q6UX27-1] ENST00000616717.4 [Q6UX27-2] ENST00000617115.4 [Q6UX27-2] G8JLN4 ENST00000614756.1 ENST00000425006.3 ENST00000618448.4 A0A2R8Y636 ENST00000611605.1 ENST00000613096.4 ENST00000612105.4 [Q6UX27-1] ENST00000610629.4 [Q6UX27-1] ENST00000613774.4 D2DJS5 ENST00000613085.4 ENST00000610575.1 ENST00000338372.7 [Q6UX27-1] ENST00000617281.4 [Q6UX27-1] H7C340 ENST00000619024.4 [Q6UX27-2] ENST00000366170.6 ENST00000610794.4 [Q6UX27-1] ENST00000612784.1 A0A0G2JPS7 ENST00000610804.4 [Q6UX27-1] ENST00000619066.1 ENST00000614572.4 ENST00000376626.5 [Q6UX27-2] ENST00000615538.1 ENST00000611293.4 [Q6UX27-1] ENST00000611985.1 ENST00000612436.4 [Q6UX27-1] ENST00000618529.4

GO_0002376	Biological process	immune system process
GO_0002764	Biological process	immune response-regulating signaling pathway
GO_0005615	Cellular component	extracellular space
GO_0005886	Cellular component	plasma membrane
GO_0005125	Molecular function	cytokine activity

VSTM1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review