THNSL2 | OmnibusX

Name	Number of supported studies	Average coverage
ciliated cell	3 studies	18% ± 1%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of THNSL2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
thymus	98%	3127.22	640 / 653	96%	26.99	578 / 605
kidney	100%	2820.66	89 / 89	92%	23.81	831 / 901
prostate	98%	3080.56	241 / 245	94%	23.06	471 / 502
liver	99%	3108.45	223 / 226	92%	17.80	373 / 406
breast	96%	2098.44	442 / 459	94%	24.17	1048 / 1118
ovary	93%	2043.95	167 / 180	87%	12.45	376 / 430
pancreas	91%	994.20	297 / 328	88%	11.40	156 / 178
skin	83%	1026.24	1494 / 1809	85%	17.55	399 / 472
adrenal gland	93%	2883.61	240 / 258	74%	10.70	170 / 230
lung	86%	1091.80	496 / 578	78%	12.90	906 / 1155
intestine	96%	2113.63	924 / 966	68%	8.22	360 / 527
uterus	92%	1696.28	156 / 170	65%	8.37	299 / 459
bladder	90%	1865.86	19 / 21	66%	8.43	331 / 504
stomach	92%	1455.40	329 / 359	55%	6.23	157 / 286
esophagus	90%	1719.59	1300 / 1445	54%	6.49	99 / 183
brain	84%	1084.18	2209 / 2642	38%	4.30	270 / 705
muscle	99%	4195.51	796 / 803	0%	0	0 / 0
eye	0%	0	0 / 0	98%	24.89	78 / 80
adipose	93%	1397.59	1120 / 1204	0%	0	0 / 0
heart	90%	1421.96	779 / 861	0%	0	0 / 0
spleen	89%	1022.15	214 / 241	0%	0	0 / 0
blood vessel	82%	831.70	1089 / 1335	0%	0	0 / 0
tonsil	0%	0	0 / 0	49%	4.39	22 / 45
lymph node	0%	0	0 / 0	28%	2.47	8 / 29
peripheral blood	4%	18.79	33 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0009071	Biological process	serine family amino acid catabolic process
GO_0007165	Biological process	signal transduction
GO_0046360	Biological process	2-oxobutyrate biosynthetic process
GO_0008150	Biological process	biological_process
GO_0016311	Biological process	dephosphorylation
GO_0005575	Cellular component	cellular_component
GO_0005615	Cellular component	extracellular space
GO_0070905	Molecular function	serine binding
GO_0004795	Molecular function	threonine synthase activity
GO_0030170	Molecular function	pyridoxal phosphate binding
GO_0005125	Molecular function	cytokine activity
GO_0003674	Molecular function	molecular_function

Gene name	THNSL2
Protein name	Threonine synthase-like 2 (TSH2) (EC 4.2.3.-) (Secreted osteoclastogenic factor of activated T-cells) (SOFAT) Threonine synthase like 2 Threonine synthase like 2 (cDNA FLJ76990) (cDNA, FLJ79480)
Synonyms
Description	FUNCTION: [Isoform 1]: Acts as a catabolic phospho-lyase on both gamma- and beta-phosphorylated substrates. Degrades O-phospho-threonine (PThr) to alpha-ketobutyrate, ammonia and phosphate (By similarity). .; FUNCTION: [Isoform SOFAT]: Potent inducer of osteoblastic production of IL6. May act to exacerbate inflammation and/or bone turnover under inflammatory conditions. .
Accessions	C9J3J1 ENST00000324166.7 [Q86YJ6-1] ENST00000496844.6 [Q86YJ6-3] ENST00000419759.5 ENST00000674334.2 [Q86YJ6-1] ENST00000449349.5 ENST00000343544.8 [Q86YJ6-2] A8K0C1 Q86YJ6 ENST00000377254.7 C9JU10

THNSL2 report