Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 6 studies | 50% ± 10% | |
| goblet cell | 6 studies | 34% ± 9% | |
| transit amplifying cell | 6 studies | 33% ± 16% | |
| enterocyte | 5 studies | 32% ± 7% | |
| progenitor cell | 5 studies | 36% ± 11% | |
| intestinal crypt stem cell | 4 studies | 37% ± 13% | |
| brush cell | 4 studies | 22% ± 3% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| intestine | 5 studies | 22% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| intestine | 90% | 4309.27 | 868 / 966 | 86% | 305.59 | 451 / 527 |
| stomach | 23% | 2.84 | 82 / 359 | 75% | 219.25 | 215 / 286 |
| uterus | 88% | 24.12 | 150 / 170 | 3% | 2.61 | 16 / 459 |
| lung | 79% | 13.90 | 455 / 578 | 12% | 11.29 | 134 / 1155 |
| ovary | 86% | 16.18 | 155 / 180 | 1% | 0.23 | 3 / 430 |
| breast | 85% | 42.44 | 390 / 459 | 1% | 0.17 | 11 / 1118 |
| adipose | 79% | 20.97 | 947 / 1204 | 0% | 0 | 0 / 0 |
| bladder | 52% | 16.38 | 11 / 21 | 26% | 91.66 | 130 / 504 |
| skin | 77% | 26.22 | 1400 / 1809 | 0% | 0.04 | 2 / 472 |
| kidney | 75% | 10.76 | 67 / 89 | 0% | 0.04 | 1 / 901 |
| esophagus | 39% | 6.01 | 557 / 1445 | 37% | 40.12 | 67 / 183 |
| blood vessel | 72% | 10.53 | 957 / 1335 | 0% | 0 | 0 / 0 |
| prostate | 70% | 12.22 | 171 / 245 | 0% | 0 | 0 / 502 |
| spleen | 68% | 10.15 | 164 / 241 | 0% | 0 | 0 / 0 |
| thymus | 60% | 8.43 | 393 / 653 | 1% | 0.22 | 9 / 605 |
| heart | 50% | 5.69 | 428 / 861 | 0% | 0 | 0 / 0 |
| brain | 47% | 7.15 | 1243 / 2642 | 0% | 0.02 | 2 / 705 |
| adrenal gland | 40% | 3.60 | 103 / 258 | 0% | 0.04 | 1 / 230 |
| pancreas | 16% | 1.36 | 52 / 328 | 15% | 10.85 | 26 / 178 |
| liver | 27% | 2.78 | 61 / 226 | 2% | 0.41 | 8 / 406 |
| muscle | 22% | 2.02 | 175 / 803 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 10% | 1.00 | 3 / 29 |
| tonsil | 0% | 0 | 0 / 0 | 7% | 0.84 | 3 / 45 |
| peripheral blood | 5% | 0.46 | 43 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0009790 | Biological process | embryo development |
| GO_0009948 | Biological process | anterior/posterior axis specification |
| GO_0060349 | Biological process | bone morphogenesis |
| GO_0006357 | Biological process | regulation of transcription by RNA polymerase II |
| GO_0009887 | Biological process | animal organ morphogenesis |
| GO_0030154 | Biological process | cell differentiation |
| GO_0014807 | Biological process | regulation of somitogenesis |
| GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
| GO_0000785 | Cellular component | chromatin |
| GO_0005634 | Cellular component | nucleus |
| GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO_0000977 | Molecular function | RNA polymerase II transcription regulatory region sequence-specific DNA binding |
| GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO_0000976 | Molecular function | transcription cis-regulatory region binding |
| GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
| GO_0008327 | Molecular function | methyl-CpG binding |
| GO_0003700 | Molecular function | DNA-binding transcription factor activity |
| GO_0005515 | Molecular function | protein binding |
| Gene name | CDX1 |
| Protein name | Homeobox protein CDX-1 (Caudal-type homeobox protein 1) CDX1 protein |
| Synonyms | |
| Description | FUNCTION: Plays a role in transcriptional regulation . Involved in activated KRAS-mediated transcriptional activation of PRKD1 in colorectal cancer (CRC) cells . Binds to the PRKD1 promoter in colorectal cancer (CRC) cells . Could play a role in the terminal differentiation of the intestine. Binds preferentially to methylated DNA . . |
| Accessions | Q14DX0 Q4VAU5 P47902 ENST00000231656.13 [P47902-1] Q4VAU3 |