CDX1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0009790Biological processembryo development
GO_0009948Biological processanterior/posterior axis specification
GO_0060349Biological processbone morphogenesis
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0009887Biological processanimal organ morphogenesis
GO_0030154Biological processcell differentiation
GO_0014807Biological processregulation of somitogenesis
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0000977Molecular functionRNA polymerase II transcription regulatory region sequence-specific DNA binding
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_0000976Molecular functiontranscription cis-regulatory region binding
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0008327Molecular functionmethyl-CpG binding
GO_0003700Molecular functionDNA-binding transcription factor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameCDX1
Protein nameHomeobox protein CDX-1 (Caudal-type homeobox protein 1)
CDX1 protein
Synonyms
DescriptionFUNCTION: Plays a role in transcriptional regulation . Involved in activated KRAS-mediated transcriptional activation of PRKD1 in colorectal cancer (CRC) cells . Binds to the PRKD1 promoter in colorectal cancer (CRC) cells . Could play a role in the terminal differentiation of the intestine. Binds preferentially to methylated DNA . .

AccessionsQ14DX0
Q4VAU5
P47902
ENST00000231656.13 [P47902-1]
Q4VAU3