RGMB report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0030509Biological processBMP signaling pathway
GO_0045893Biological processpositive regulation of DNA-templated transcription
GO_0007155Biological processcell adhesion
GO_0045121Cellular componentmembrane raft
GO_0098552Cellular componentside of membrane
GO_0005886Cellular componentplasma membrane
GO_0005793Cellular componentendoplasmic reticulum-Golgi intermediate compartment
GO_0015026Molecular functioncoreceptor activity
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameRGMB
Protein nameRepulsive guidance molecule BMP co-receptor b
Repulsive guidance molecule B (DRG11-responsive axonal guidance and outgrowth of neurite) (DRAGON)
Synonyms
DescriptionFUNCTION: Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system (By similarity). Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling (By similarity). Promotes neuronal adhesion (By similarity). May inhibit neurite outgrowth. .

AccessionsJ3KNF6
ENST00000513185.3
ENST00000308234.11
Q6NW40