Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| intestinal crypt stem cell | 5 studies | 35% ± 18% | |
| neuron | 5 studies | 28% ± 14% | |
| GABAergic neuron | 5 studies | 28% ± 6% | |
| epithelial cell | 4 studies | 18% ± 2% | |
| glutamatergic neuron | 4 studies | 36% ± 10% | |
| oligodendrocyte precursor cell | 4 studies | 29% ± 7% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| brain | 4 studies | 26% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 2943.87 | 1445 / 1445 | 98% | 6.61 | 180 / 183 |
| prostate | 100% | 1322.17 | 245 / 245 | 98% | 11.90 | 492 / 502 |
| stomach | 100% | 2366.85 | 359 / 359 | 98% | 9.67 | 279 / 286 |
| brain | 96% | 836.57 | 2526 / 2642 | 100% | 19.23 | 703 / 705 |
| breast | 100% | 597.75 | 457 / 459 | 95% | 5.56 | 1067 / 1118 |
| intestine | 100% | 1303.23 | 966 / 966 | 95% | 8.82 | 499 / 527 |
| thymus | 100% | 703.95 | 650 / 653 | 94% | 6.55 | 566 / 605 |
| bladder | 100% | 853.76 | 21 / 21 | 93% | 5.69 | 469 / 504 |
| uterus | 100% | 644.62 | 170 / 170 | 92% | 5.46 | 423 / 459 |
| ovary | 100% | 1114.86 | 180 / 180 | 92% | 4.55 | 394 / 430 |
| skin | 100% | 1847.87 | 1807 / 1809 | 91% | 8.00 | 429 / 472 |
| lung | 99% | 612.39 | 571 / 578 | 90% | 4.79 | 1041 / 1155 |
| pancreas | 96% | 400.82 | 316 / 328 | 91% | 3.51 | 162 / 178 |
| adrenal gland | 58% | 178.91 | 149 / 258 | 78% | 13.33 | 180 / 230 |
| kidney | 61% | 205.04 | 54 / 89 | 46% | 1.46 | 411 / 901 |
| muscle | 100% | 839.60 | 800 / 803 | 0% | 0 | 0 / 0 |
| adipose | 99% | 520.89 | 1194 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 98% | 434.61 | 1307 / 1335 | 0% | 0 | 0 / 0 |
| heart | 97% | 446.82 | 833 / 861 | 0% | 0 | 0 / 0 |
| spleen | 97% | 433.02 | 233 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 5.05 | 43 / 45 |
| liver | 55% | 184.06 | 124 / 226 | 31% | 1.37 | 125 / 406 |
| eye | 0% | 0 | 0 / 0 | 84% | 4.84 | 67 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 14% | 0.32 | 4 / 29 |
| peripheral blood | 9% | 28.88 | 80 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007165 | Biological process | signal transduction |
| GO_0030509 | Biological process | BMP signaling pathway |
| GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
| GO_0007155 | Biological process | cell adhesion |
| GO_0045121 | Cellular component | membrane raft |
| GO_0098552 | Cellular component | side of membrane |
| GO_0005886 | Cellular component | plasma membrane |
| GO_0005793 | Cellular component | endoplasmic reticulum-Golgi intermediate compartment |
| GO_0015026 | Molecular function | coreceptor activity |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | RGMB |
| Protein name | Repulsive guidance molecule BMP co-receptor b Repulsive guidance molecule B (DRG11-responsive axonal guidance and outgrowth of neurite) (DRAGON) |
| Synonyms | |
| Description | FUNCTION: Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system (By similarity). Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling (By similarity). Promotes neuronal adhesion (By similarity). May inhibit neurite outgrowth. . |
| Accessions | J3KNF6 ENST00000513185.3 ENST00000308234.11 Q6NW40 |