I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| oligodendrocyte | 7 studies | 27% ± 11% | |
| epithelial cell | 5 studies | 33% ± 9% | |
| intestinal crypt stem cell | 3 studies | 19% ± 2% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| oligodendrocyte | 7 studies | 27% ± 11% | |
| epithelial cell | 5 studies | 33% ± 9% | |
| intestinal crypt stem cell | 3 studies | 19% ± 2% |
Insufficient scRNA-seq data for expression of GJB1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 100% | 14075.50 | 226 / 226 | 99% | 215.02 | 401 / 406 |
| pancreas | 100% | 4613.09 | 328 / 328 | 84% | 35.85 | 149 / 178 |
| stomach | 74% | 712.57 | 264 / 359 | 87% | 51.83 | 248 / 286 |
| prostate | 62% | 408.46 | 152 / 245 | 95% | 74.52 | 475 / 502 |
| kidney | 99% | 1626.35 | 88 / 89 | 53% | 12.41 | 476 / 901 |
| intestine | 45% | 1180.58 | 437 / 966 | 89% | 57.81 | 470 / 527 |
| brain | 83% | 1793.55 | 2185 / 2642 | 43% | 13.73 | 304 / 705 |
| skin | 1% | 2.72 | 18 / 1809 | 84% | 91.72 | 397 / 472 |
| ovary | 0% | 0 | 0 / 180 | 64% | 19.84 | 274 / 430 |
| esophagus | 1% | 3.12 | 9 / 1445 | 35% | 13.65 | 64 / 183 |
| lung | 4% | 9.98 | 21 / 578 | 28% | 9.81 | 327 / 1155 |
| bladder | 0% | 0 | 0 / 21 | 28% | 19.65 | 139 / 504 |
| breast | 8% | 43.35 | 39 / 459 | 11% | 2.94 | 127 / 1118 |
| uterus | 5% | 30.63 | 9 / 170 | 13% | 4.65 | 58 / 459 |
| eye | 0% | 0 | 0 / 0 | 8% | 1.15 | 6 / 80 |
| tonsil | 0% | 0 | 0 / 0 | 2% | 0.42 | 1 / 45 |
| adrenal gland | 0% | 0 | 0 / 258 | 1% | 0.87 | 3 / 230 |
| adipose | 1% | 3.82 | 9 / 1204 | 0% | 0 | 0 / 0 |
| peripheral blood | 1% | 3.78 | 5 / 929 | 0% | 0 | 0 / 0 |
| spleen | 0% | 15.56 | 1 / 241 | 0% | 0 | 0 / 0 |
| heart | 0% | 0.25 | 1 / 861 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 0.64 | 1 / 1335 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| muscle | 0% | 0 | 0 / 803 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| thymus | 0% | 0 | 0 / 653 | 0% | 0 | 0 / 605 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0007267 | Biological process | cell-cell signaling |
| GO_1905867 | Biological process | epididymis development |
| GO_0016264 | Biological process | gap junction assembly |
| GO_0007399 | Biological process | nervous system development |
| GO_0055085 | Biological process | transmembrane transport |
| GO_0015868 | Biological process | purine ribonucleotide transport |
| GO_0005922 | Cellular component | connexin complex |
| GO_0016328 | Cellular component | lateral plasma membrane |
| GO_0005789 | Cellular component | endoplasmic reticulum membrane |
| GO_0005243 | Molecular function | gap junction channel activity |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | GJB1 |
| Protein name | Gap junction beta-1 protein Gap junction beta-1 protein (Connexin-32) (Cx32) (GAP junction 28 kDa liver protein) |
| Synonyms | CX32 |
| Description | FUNCTION: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. |
| Accessions | ENST00000675209.1 ENST00000675609.1 C9JWU8 ENST00000361726.7 ENST00000447581.2 ENST00000647424.1 ENST00000374029.2 P08034 ENST00000674549.1 ENST00000646835.1 ENST00000447581 A0A2R8YD01 ENST00000674844.1 ENST00000645009 ENST00000675368.1 ENST00000645009.2 |
