Name | Number of supported studies | Average coverage | |
---|---|---|---|
ciliated cell | 12 studies | 57% ± 13% | |
club cell | 11 studies | 60% ± 25% | |
epithelial cell | 11 studies | 58% ± 26% | |
goblet cell | 10 studies | 63% ± 23% | |
type II pneumocyte | 9 studies | 59% ± 24% | |
enterocyte | 9 studies | 51% ± 27% | |
respiratory goblet cell | 8 studies | 75% ± 22% | |
secretory cell | 7 studies | 60% ± 17% | |
mucus secreting cell | 6 studies | 68% ± 28% | |
duct epithelial cell | 5 studies | 83% ± 13% | |
intestinal crypt stem cell | 5 studies | 67% ± 29% | |
basal cell | 5 studies | 31% ± 19% | |
deuterosomal cell | 4 studies | 72% ± 7% | |
transit amplifying cell | 4 studies | 93% ± 6% | |
paneth cell | 3 studies | 75% ± 16% | |
kidney loop of Henle epithelial cell | 3 studies | 28% ± 8% | |
progenitor cell | 3 studies | 92% ± 8% | |
progenitor cell of mammary luminal epithelium | 3 studies | 44% ± 21% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
pancreas | 84% | 1672.46 | 275 / 328 | 66% | 412.05 | 117 / 178 |
stomach | 78% | 24310.89 | 280 / 359 | 71% | 1212.38 | 203 / 286 |
intestine | 70% | 104778.18 | 673 / 966 | 78% | 2038.35 | 412 / 527 |
kidney | 100% | 21028.02 | 89 / 89 | 42% | 631.46 | 382 / 901 |
lung | 85% | 11344.64 | 492 / 578 | 41% | 470.26 | 477 / 1155 |
liver | 100% | 2465.78 | 225 / 226 | 20% | 64.32 | 82 / 406 |
prostate | 51% | 2528.33 | 125 / 245 | 28% | 108.80 | 140 / 502 |
bladder | 43% | 2245.00 | 9 / 21 | 30% | 630.27 | 152 / 504 |
breast | 57% | 6815.71 | 263 / 459 | 7% | 37.22 | 80 / 1118 |
esophagus | 14% | 988.03 | 197 / 1445 | 38% | 817.38 | 69 / 183 |
uterus | 15% | 1011.19 | 26 / 170 | 15% | 242.22 | 71 / 459 |
peripheral blood | 14% | 339.37 | 132 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 7% | 8.77 | 2 / 29 |
ovary | 2% | 55.67 | 4 / 180 | 4% | 15.47 | 19 / 430 |
skin | 3% | 21.54 | 48 / 1809 | 0% | 2.94 | 1 / 472 |
tonsil | 0% | 0 | 0 / 0 | 2% | 3.28 | 1 / 45 |
spleen | 1% | 10.85 | 3 / 241 | 0% | 0 | 0 / 0 |
thymus | 1% | 13.30 | 6 / 653 | 0% | 0.29 | 1 / 605 |
adrenal gland | 1% | 112.88 | 2 / 258 | 0% | 0 | 0 / 230 |
adipose | 1% | 15.76 | 8 / 1204 | 0% | 0 | 0 / 0 |
muscle | 0% | 23.38 | 4 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 0% | 4.89 | 4 / 1335 | 0% | 0 | 0 / 0 |
heart | 0% | 3.42 | 2 / 861 | 0% | 0 | 0 / 0 |
brain | 0% | 2.41 | 5 / 2642 | 0% | 0 | 0 / 705 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0038093 | Biological process | Fc receptor signaling pathway |
GO_0007173 | Biological process | epidermal growth factor receptor signaling pathway |
GO_0001580 | Biological process | detection of chemical stimulus involved in sensory perception of bitter taste |
GO_0002415 | Biological process | immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor |
GO_0043113 | Biological process | receptor clustering |
GO_0005615 | Cellular component | extracellular space |
GO_0035577 | Cellular component | azurophil granule membrane |
GO_0070062 | Cellular component | extracellular exosome |
GO_0043235 | Cellular component | receptor complex |
GO_0005886 | Cellular component | plasma membrane |
GO_0071751 | Cellular component | secretory IgA immunoglobulin complex |
GO_0004888 | Molecular function | transmembrane signaling receptor activity |
GO_0001790 | Molecular function | polymeric immunoglobulin binding |
GO_0001792 | Molecular function | polymeric immunoglobulin receptor activity |
Gene name | PIGR |
Protein name | Polymeric immunoglobulin receptor (PIgR) (Poly-Ig receptor) (Hepatocellular carcinoma-associated protein TB6) [Cleaved into: Secretory component] Polymeric immunoglobulin receptor |
Synonyms | |
Description | FUNCTION: [Polymeric immunoglobulin receptor]: Mediates selective transcytosis of polymeric IgA and IgM across mucosal epithelial cells. Binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process, a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment. .; FUNCTION: [Secretory component]: Through its N-linked glycans ensures anchoring of secretory IgA (sIgA) molecules to mucus lining the epithelial surface to neutralize extracellular pathogens . On its own (free form) may act as a non-specific microbial scavenger to prevent pathogen interaction with epithelial cells . . |
Accessions | P01833 ENST00000356495.5 Q8TE27 |