Name | secretory IgA immunoglobulin complex |
ID | GO_0071751 |
collection_id | Cellular component |
Exact synonym | sIgA antibody, secretory IgA antibody |
Description | A polymeric IgA immunoglobulin complex that is complexed with one chain of secretory component (SC). Polymeric IgA is present in mucosal areas, having been transported via a transcytosis mechanism in mucosal epithelial cells relying on the polymeric Ig receptor, a portion of which then remains bound to the polymeric IgA as secretory component. |
Comment | Note that an IgA immunoglobulin complex has the function of antigen binding if a suitable antigen is available. In human only the IgA1 isotype in the polymeric form is capable of becoming secretory IgA. |
External URL | |
Genes |