Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| enterocyte | 7 studies | 44% ± 17% | |
| intestinal crypt stem cell | 4 studies | 51% ± 10% | |
| epithelial cell | 4 studies | 29% ± 8% | |
| transit amplifying cell | 3 studies | 43% ± 7% | |
| progenitor cell | 3 studies | 41% ± 18% |
Insufficient scRNA-seq data for expression of CCL25 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| liver | 60% | 5.79 | 135 / 226 | 58% | 64.34 | 236 / 406 |
| brain | 71% | 9.10 | 1869 / 2642 | 29% | 0.71 | 205 / 705 |
| spleen | 95% | 21.26 | 228 / 241 | 0% | 0 | 0 / 0 |
| ovary | 28% | 1.79 | 51 / 180 | 65% | 4.38 | 279 / 430 |
| intestine | 36% | 525.45 | 350 / 966 | 29% | 23.19 | 152 / 527 |
| thymus | 32% | 2.38 | 211 / 653 | 29% | 982.51 | 176 / 605 |
| stomach | 9% | 0.90 | 33 / 359 | 51% | 78.06 | 145 / 286 |
| prostate | 43% | 3.20 | 105 / 245 | 9% | 0.44 | 46 / 502 |
| lung | 19% | 1.09 | 111 / 578 | 25% | 10.09 | 289 / 1155 |
| lymph node | 0% | 0 | 0 / 0 | 41% | 2.27 | 12 / 29 |
| peripheral blood | 40% | 48.71 | 376 / 929 | 0% | 0 | 0 / 0 |
| breast | 28% | 1.72 | 128 / 459 | 9% | 0.37 | 106 / 1118 |
| uterus | 21% | 1.13 | 36 / 170 | 16% | 3.09 | 74 / 459 |
| skin | 24% | 1.45 | 433 / 1809 | 13% | 0.27 | 61 / 472 |
| esophagus | 6% | 0.72 | 83 / 1445 | 30% | 52.81 | 54 / 183 |
| tonsil | 0% | 0 | 0 / 0 | 29% | 0.74 | 13 / 45 |
| kidney | 24% | 1.15 | 21 / 89 | 4% | 0.11 | 36 / 901 |
| bladder | 14% | 0.71 | 3 / 21 | 10% | 4.66 | 52 / 504 |
| adrenal gland | 8% | 0.37 | 20 / 258 | 10% | 0.24 | 23 / 230 |
| adipose | 16% | 0.95 | 192 / 1204 | 0% | 0 | 0 / 0 |
| pancreas | 4% | 0.19 | 14 / 328 | 11% | 4.26 | 20 / 178 |
| blood vessel | 9% | 0.52 | 121 / 1335 | 0% | 0 | 0 / 0 |
| heart | 5% | 0.26 | 44 / 861 | 0% | 0 | 0 / 0 |
| muscle | 3% | 0.13 | 24 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 3% | 0.05 | 2 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006954 | Biological process | inflammatory response |
| GO_0043547 | Biological process | positive regulation of GTPase activity |
| GO_0001954 | Biological process | positive regulation of cell-matrix adhesion |
| GO_0006935 | Biological process | chemotaxis |
| GO_0006955 | Biological process | immune response |
| GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
| GO_0070098 | Biological process | chemokine-mediated signaling pathway |
| GO_0030335 | Biological process | positive regulation of cell migration |
| GO_0048245 | Biological process | eosinophil chemotaxis |
| GO_1903237 | Biological process | negative regulation of leukocyte tethering or rolling |
| GO_0061844 | Biological process | antimicrobial humoral immune response mediated by antimicrobial peptide |
| GO_0060326 | Biological process | cell chemotaxis |
| GO_0007166 | Biological process | cell surface receptor signaling pathway |
| GO_0005615 | Cellular component | extracellular space |
| GO_0005576 | Cellular component | extracellular region |
| GO_0008009 | Molecular function | chemokine activity |
| GO_0048020 | Molecular function | CCR chemokine receptor binding |
| GO_0005179 | Molecular function | hormone activity |
| GO_0031735 | Molecular function | CCR10 chemokine receptor binding |
| GO_0042379 | Molecular function | chemokine receptor binding |
| GO_0005515 | Molecular function | protein binding |
| Gene name | CCL25 |
| Protein name | C-C motif chemokine ligand 25 C-C motif chemokine 25 C-C motif chemokine 25 (Chemokine TECK) (Small-inducible cytokine A25) (Thymus-expressed chemokine) CCL25 protein |
| Synonyms | SCYA25 TECK |
| Description | FUNCTION: Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Isoform 2 is an antagonist of isoform 1. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. |
| Accessions | O15444 ENST00000680450.1 [O15444-3] F8VWI0 ENST00000390669.7 [O15444-1] ENST00000253451.9 [O15444-3] ENST00000680507.1 ENST00000458625.5 ENST00000681526.1 [O15444-3] ENST00000680646.1 [O15444-1] ENST00000315626 A0A7P0TBH2 ENST00000680506.1 [O15444-1] Q08AK2 C9JDZ7 ENST00000315626.6 [O15444-1] |
