I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| smooth muscle cell | 4 studies | 22% ± 3% | |
| epithelial cell | 4 studies | 27% ± 12% | |
| intestinal crypt stem cell | 4 studies | 30% ± 11% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| smooth muscle cell | 4 studies | 22% ± 3% | |
| epithelial cell | 4 studies | 27% ± 12% | |
| intestinal crypt stem cell | 4 studies | 30% ± 11% |
Insufficient scRNA-seq data for expression of ALDH1B1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| intestine | 99% | 6245.82 | 955 / 966 | 99% | 154.75 | 522 / 527 |
| liver | 98% | 4969.01 | 221 / 226 | 99% | 112.99 | 403 / 406 |
| bladder | 95% | 12514.76 | 20 / 21 | 93% | 81.00 | 467 / 504 |
| kidney | 88% | 3378.04 | 78 / 89 | 91% | 51.57 | 819 / 901 |
| uterus | 86% | 5562.02 | 147 / 170 | 87% | 63.53 | 399 / 459 |
| prostate | 71% | 3791.33 | 175 / 245 | 100% | 72.87 | 500 / 502 |
| stomach | 66% | 3381.11 | 236 / 359 | 100% | 130.95 | 285 / 286 |
| esophagus | 75% | 7514.34 | 1080 / 1445 | 90% | 47.15 | 165 / 183 |
| breast | 60% | 1035.61 | 276 / 459 | 98% | 56.06 | 1096 / 1118 |
| ovary | 49% | 1090.72 | 89 / 180 | 98% | 43.33 | 422 / 430 |
| lung | 44% | 727.50 | 252 / 578 | 97% | 51.32 | 1121 / 1155 |
| thymus | 54% | 926.23 | 354 / 653 | 83% | 24.90 | 505 / 605 |
| adrenal gland | 74% | 1176.30 | 190 / 258 | 62% | 18.01 | 142 / 230 |
| skin | 43% | 1312.93 | 781 / 1809 | 86% | 53.27 | 406 / 472 |
| pancreas | 19% | 247.02 | 61 / 328 | 97% | 52.67 | 172 / 178 |
| eye | 0% | 0 | 0 / 0 | 100% | 175.74 | 80 / 80 |
| blood vessel | 100% | 15585.12 | 1331 / 1335 | 0% | 0 | 0 / 0 |
| brain | 2% | 28.78 | 61 / 2642 | 97% | 28.81 | 686 / 705 |
| muscle | 97% | 3581.87 | 776 / 803 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 87% | 29.47 | 39 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 86% | 27.81 | 25 / 29 |
| adipose | 81% | 1970.27 | 981 / 1204 | 0% | 0 | 0 / 0 |
| heart | 40% | 720.65 | 343 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 19% | 562.92 | 174 / 929 | 0% | 0 | 0 / 0 |
| spleen | 16% | 199.82 | 38 / 241 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0005975 | Biological process | carbohydrate metabolic process |
| GO_0006068 | Biological process | ethanol catabolic process |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0005829 | Cellular component | cytosol |
| GO_0005759 | Cellular component | mitochondrial matrix |
| GO_0005739 | Cellular component | mitochondrion |
| GO_0051287 | Molecular function | NAD binding |
| GO_0004029 | Molecular function | aldehyde dehydrogenase (NAD+) activity |
| GO_0043878 | Molecular function | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity |
| Gene name | ALDH1B1 |
| Protein name | Aldehyde dehydrogenase X, mitochondrial (EC 1.2.1.3) (Aldehyde dehydrogenase family 1 member B1) Aldehyde dehydrogenase X, mitochondrial (EC 1.2.1.3) (Aldehyde dehydrogenase 5) (Aldehyde dehydrogenase family 1 member B1) |
| Synonyms | ALDHX ALDH5 |
| Description | FUNCTION: ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation. |
| Accessions | P30837 A0A0U1RQK9 ENST00000377698.4 ENST00000635162.1 |
