Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| astrocyte | 13 studies | 37% ± 17% | |
| oligodendrocyte precursor cell | 11 studies | 47% ± 16% | |
| glutamatergic neuron | 10 studies | 36% ± 24% | |
| oligodendrocyte | 10 studies | 29% ± 11% | |
| GABAergic neuron | 7 studies | 39% ± 19% | |
| adipocyte | 7 studies | 27% ± 12% | |
| neuron | 5 studies | 33% ± 11% | |
| interneuron | 5 studies | 41% ± 20% | |
| epithelial cell | 5 studies | 26% ± 8% | |
| endothelial cell | 4 studies | 35% ± 15% | |
| granule cell | 4 studies | 33% ± 1% | |
| cardiac muscle cell | 4 studies | 23% ± 4% | |
| GABAergic interneuron | 3 studies | 26% ± 12% | |
| GABAergic amacrine cell | 3 studies | 19% ± 3% | |
| fibroblast | 3 studies | 22% ± 2% | |
| club cell | 3 studies | 20% ± 5% | |
| type I pneumocyte | 3 studies | 22% ± 5% | |
| type II pneumocyte | 3 studies | 19% ± 5% | |
| goblet cell | 3 studies | 28% ± 17% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 100% | 5864.13 | 245 / 245 | 99% | 12.36 | 499 / 502 |
| brain | 100% | 1734.81 | 2631 / 2642 | 99% | 10.39 | 698 / 705 |
| thymus | 100% | 2834.07 | 653 / 653 | 94% | 5.53 | 571 / 605 |
| breast | 100% | 1715.78 | 457 / 459 | 95% | 7.24 | 1060 / 1118 |
| ovary | 100% | 2371.43 | 180 / 180 | 94% | 6.21 | 404 / 430 |
| esophagus | 98% | 1308.49 | 1415 / 1445 | 96% | 7.28 | 175 / 183 |
| kidney | 100% | 1356.46 | 89 / 89 | 92% | 4.68 | 826 / 901 |
| intestine | 100% | 2135.04 | 966 / 966 | 89% | 4.26 | 470 / 527 |
| skin | 99% | 1090.39 | 1783 / 1809 | 89% | 5.82 | 422 / 472 |
| stomach | 100% | 1065.45 | 358 / 359 | 88% | 4.62 | 252 / 286 |
| pancreas | 94% | 575.50 | 308 / 328 | 92% | 4.34 | 163 / 178 |
| lung | 99% | 964.36 | 570 / 578 | 87% | 4.11 | 1003 / 1155 |
| bladder | 100% | 2285.90 | 21 / 21 | 85% | 4.01 | 427 / 504 |
| adrenal gland | 100% | 2214.69 | 258 / 258 | 83% | 3.44 | 190 / 230 |
| uterus | 100% | 2643.48 | 170 / 170 | 73% | 3.52 | 334 / 459 |
| spleen | 100% | 1393.30 | 241 / 241 | 0% | 0 | 0 / 0 |
| blood vessel | 100% | 1947.44 | 1333 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 100% | 1599.62 | 800 / 803 | 0% | 0 | 0 / 0 |
| adipose | 99% | 977.74 | 1186 / 1204 | 0% | 0 | 0 / 0 |
| heart | 93% | 1035.76 | 803 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 89% | 4.55 | 71 / 80 |
| tonsil | 0% | 0 | 0 / 0 | 76% | 4.67 | 34 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 72% | 2.93 | 21 / 29 |
| peripheral blood | 28% | 755.66 | 258 / 929 | 0% | 0 | 0 / 0 |
| liver | 4% | 15.24 | 9 / 226 | 5% | 0.17 | 22 / 406 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0006338 | Biological process | chromatin remodeling |
| GO_0070200 | Biological process | establishment of protein localization to telomere |
| GO_0000723 | Biological process | telomere maintenance |
| GO_1904791 | Biological process | negative regulation of shelterin complex assembly |
| GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
| GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
| GO_0000781 | Cellular component | chromosome, telomeric region |
| GO_1990904 | Cellular component | ribonucleoprotein complex |
| GO_0000785 | Cellular component | chromatin |
| GO_0005634 | Cellular component | nucleus |
| GO_0003677 | Molecular function | DNA binding |
| GO_0120325 | Molecular function | NuRD complex binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0046872 | Molecular function | metal ion binding |
| Gene name | ZNF827 |
| Protein name | Zinc finger protein 827 |
| Synonyms | LOC152485 hCG_38981 |
| Description | FUNCTION: As part of a ribonucleoprotein complex composed at least of HNRNPK, HNRNPL and the circular RNA circZNF827 that nucleates the complex on chromatin, may negatively regulate the transcription of genes involved in neuronal differentiation . Could also recruit the nucleosome remodeling and histone deacetylase/NuRD complex to telomeric regions of chromosomes to regulate chromatin remodeling as part of telomere maintenance . . |
| Accessions | A0A5F9ZGT0 A0A5F9ZGW8 Q17R98 ENST00000503462.3 ENST00000511659.2 ENST00000652097.1 A0A5F9ZHK5 ENST00000673178.1 ENST00000513320.5 ENST00000513840.2 ENST00000379448.9 [Q17R98-2] ENST00000508784.6 [Q17R98-1] H0Y9M2 A0A590UJE4 A0A494C0H4 ENST00000509940.1 G5E9Z1 ENST00000655597.2 H0Y9K9 ENST00000656985.1 [Q17R98-2] |