ZNF827 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006338Biological processchromatin remodeling
GO_0070200Biological processestablishment of protein localization to telomere
GO_0000723Biological processtelomere maintenance
GO_1904791Biological processnegative regulation of shelterin complex assembly
GO_0045892Biological processnegative regulation of DNA-templated transcription
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0000781Cellular componentchromosome, telomeric region
GO_1990904Cellular componentribonucleoprotein complex
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0003677Molecular functionDNA binding
GO_0120325Molecular functionNuRD complex binding
GO_0005515Molecular functionprotein binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene nameZNF827
Protein nameZinc finger protein 827
SynonymsLOC152485
hCG_38981
DescriptionFUNCTION: As part of a ribonucleoprotein complex composed at least of HNRNPK, HNRNPL and the circular RNA circZNF827 that nucleates the complex on chromatin, may negatively regulate the transcription of genes involved in neuronal differentiation . Could also recruit the nucleosome remodeling and histone deacetylase/NuRD complex to telomeric regions of chromosomes to regulate chromatin remodeling as part of telomere maintenance . .

AccessionsA0A5F9ZGT0
A0A5F9ZGW8
Q17R98
ENST00000503462.3
ENST00000511659.2
ENST00000652097.1
A0A5F9ZHK5
ENST00000673178.1
ENST00000513320.5
ENST00000513840.2
ENST00000379448.9 [Q17R98-2]
ENST00000508784.6 [Q17R98-1]
H0Y9M2
A0A590UJE4
A0A494C0H4
ENST00000509940.1
G5E9Z1
ENST00000655597.2
H0Y9K9
ENST00000656985.1 [Q17R98-2]