WRNIP1 | OmnibusX

Name	Number of supported studies	Average coverage
endothelial cell	5 studies	24% ± 5%	Explore
epithelial cell	5 studies	25% ± 6%	Explore
oligodendrocyte precursor cell	4 studies	31% ± 11%	Explore
ciliated cell	3 studies	23% ± 4%	Explore
GABAergic neuron	3 studies	34% ± 6%	Explore
glutamatergic neuron	3 studies	44% ± 7%	Explore
transit amplifying cell	3 studies	21% ± 5%	Explore
oligodendrocyte	3 studies	22% ± 4%	Explore

Name	Number of supported studies	Average coverage
brain	4 studies	33% ± 5%	Explore
liver	3 studies	18% ± 2%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	2975.32	1445 / 1445	100%	55.66	183 / 183
lung	100%	2877.72	578 / 578	100%	57.40	1155 / 1155
ovary	100%	2596.15	180 / 180	100%	54.79	430 / 430
pancreas	100%	2051.70	328 / 328	100%	46.70	178 / 178
prostate	100%	2621.14	245 / 245	100%	57.63	502 / 502
stomach	100%	1995.91	359 / 359	100%	57.22	286 / 286
brain	100%	2924.68	2639 / 2642	100%	46.56	705 / 705
breast	100%	2327.39	459 / 459	100%	60.30	1116 / 1118
skin	100%	3074.88	1809 / 1809	100%	67.43	471 / 472
uterus	100%	2620.28	170 / 170	100%	71.48	458 / 459
intestine	100%	2541.36	966 / 966	100%	58.99	525 / 527
bladder	100%	2499.38	21 / 21	100%	59.32	502 / 504
thymus	100%	3347.38	653 / 653	100%	64.86	602 / 605
kidney	100%	2385.51	89 / 89	99%	34.39	895 / 901
adrenal gland	100%	2606.61	258 / 258	99%	41.10	227 / 230
liver	100%	1438.35	226 / 226	98%	33.54	396 / 406
adipose	100%	2135.85	1204 / 1204	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	52.63	29 / 29
muscle	100%	2272.44	803 / 803	0%	0	0 / 0
spleen	100%	2447.69	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	67.42	45 / 45
ureter	0%	0	0 / 0	100%	40.47	1 / 1
blood vessel	100%	2788.72	1334 / 1335	0%	0	0 / 0
heart	99%	1959.85	853 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	99%	37.86	79 / 80
peripheral blood	84%	1066.33	785 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0032508	Biological process	DNA duplex unwinding
GO_0030174	Biological process	regulation of DNA-templated DNA replication initiation
GO_0000731	Biological process	DNA synthesis involved in DNA repair
GO_0045087	Biological process	innate immune response
GO_0006261	Biological process	DNA-templated DNA replication
GO_0000781	Cellular component	chromosome, telomeric region
GO_0048471	Cellular component	perinuclear region of cytoplasm
GO_0016020	Cellular component	membrane
GO_0005634	Cellular component	nucleus
GO_0003677	Molecular function	DNA binding
GO_0008047	Molecular function	enzyme activator activity
GO_0046872	Molecular function	metal ion binding
GO_0005524	Molecular function	ATP binding
GO_0005515	Molecular function	protein binding
GO_0016887	Molecular function	ATP hydrolysis activity
GO_0017116	Molecular function	single-stranded DNA helicase activity
GO_0042802	Molecular function	identical protein binding

Gene name	WRNIP1
Protein name	ATPase WRNIP1 (EC 3.6.1.-) (Werner helicase-interacting protein 1)
Synonyms	WHIP
Description	FUNCTION: Functions as a modulator of initiation or reinitiation events during DNA polymerase delta-mediated DNA synthesis. In the presence of ATP, stimulation of DNA polymerase delta-mediated DNA synthesis is decreased. Also plays a role in the innate immune defense against viruses. Stabilizes the RIGI dsRNA interaction and promotes RIGI 'Lys-63'-linked polyubiquitination. In turn, RIGI transmits the signal through mitochondrial MAVS. .
Accessions	ENST00000380771.8 [Q96S55-2] ENST00000380773.9 [Q96S55-1] ENST00000380764.1 [Q96S55-4] Q96S55 ENST00000380769.8 [Q96S55-3] ENST00000618555.4 [Q96S55-1]

WRNIP1 report