Name | Number of supported studies | Average coverage | |
---|---|---|---|
glutamatergic neuron | 7 studies | 41% ± 26% | |
GABAergic neuron | 7 studies | 40% ± 20% | |
astrocyte | 7 studies | 28% ± 10% | |
endothelial cell | 6 studies | 26% ± 8% | |
oligodendrocyte | 6 studies | 25% ± 6% | |
retinal rod cell | 5 studies | 20% ± 4% | |
oligodendrocyte precursor cell | 5 studies | 27% ± 10% | |
interneuron | 5 studies | 40% ± 22% | |
neuron | 4 studies | 24% ± 10% | |
epithelial cell | 4 studies | 28% ± 6% | |
GABAergic interneuron | 3 studies | 20% ± 2% | |
microglial cell | 3 studies | 21% ± 1% | |
macrophage | 3 studies | 18% ± 2% | |
transit amplifying cell | 3 studies | 33% ± 18% | |
adipocyte | 3 studies | 21% ± 2% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
esophagus | 100% | 1010.62 | 1445 / 1445 | 100% | 27.00 | 183 / 183 |
ovary | 100% | 1743.51 | 180 / 180 | 100% | 29.55 | 430 / 430 |
uterus | 100% | 1456.38 | 170 / 170 | 100% | 28.28 | 459 / 459 |
brain | 100% | 1494.80 | 2641 / 2642 | 100% | 33.11 | 705 / 705 |
breast | 100% | 1396.04 | 459 / 459 | 100% | 33.93 | 1117 / 1118 |
prostate | 100% | 1296.83 | 245 / 245 | 100% | 21.61 | 501 / 502 |
bladder | 100% | 1295.90 | 21 / 21 | 99% | 21.29 | 501 / 504 |
thymus | 100% | 1230.16 | 653 / 653 | 99% | 27.05 | 601 / 605 |
lung | 99% | 1086.32 | 574 / 578 | 100% | 24.19 | 1155 / 1155 |
intestine | 100% | 1119.76 | 966 / 966 | 99% | 21.58 | 523 / 527 |
adrenal gland | 100% | 2094.72 | 258 / 258 | 99% | 27.97 | 228 / 230 |
stomach | 99% | 820.41 | 357 / 359 | 99% | 22.79 | 284 / 286 |
kidney | 100% | 999.46 | 89 / 89 | 98% | 21.37 | 886 / 901 |
pancreas | 98% | 644.03 | 323 / 328 | 99% | 15.88 | 176 / 178 |
skin | 100% | 1397.60 | 1809 / 1809 | 96% | 21.72 | 452 / 472 |
liver | 99% | 647.37 | 224 / 226 | 96% | 15.13 | 389 / 406 |
adipose | 100% | 1335.81 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 18.86 | 29 / 29 |
spleen | 100% | 1303.32 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 25.76 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 7.08 | 1 / 1 |
muscle | 100% | 1504.21 | 802 / 803 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 1153.57 | 1333 / 1335 | 0% | 0 | 0 / 0 |
heart | 98% | 1120.11 | 840 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 89% | 14.30 | 71 / 80 |
peripheral blood | 74% | 817.76 | 685 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0061351 | Biological process | neural precursor cell proliferation |
GO_0006270 | Biological process | DNA replication initiation |
GO_0006275 | Biological process | regulation of DNA replication |
GO_0006260 | Biological process | DNA replication |
GO_0014009 | Biological process | glial cell proliferation |
GO_0000808 | Cellular component | origin recognition complex |
GO_0005664 | Cellular component | nuclear origin of replication recognition complex |
GO_0000781 | Cellular component | chromosome, telomeric region |
GO_0005654 | Cellular component | nucleoplasm |
GO_0000785 | Cellular component | chromatin |
GO_0016604 | Cellular component | nuclear body |
GO_0031261 | Cellular component | DNA replication preinitiation complex |
GO_0005656 | Cellular component | nuclear pre-replicative complex |
GO_0005634 | Cellular component | nucleus |
GO_0005515 | Molecular function | protein binding |
GO_0003688 | Molecular function | DNA replication origin binding |
Gene name | ORC3 |
Protein name | Origin recognition complex subunit 3 (Origin recognition complex subunit Latheo) Origin recognition complex subunit 3 |
Synonyms | LATHEO ORC3L |
Description | FUNCTION: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3. . |
Accessions | U3KQL3 Q9UBD5 ENST00000508875.1 ENST00000546266.5 [Q9UBD5-3] ENST00000392844.8 [Q9UBD5-1] ENST00000257789.4 [Q9UBD5-2] |