CBX1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0006974Biological processDNA damage response
GO_0031507Biological processheterochromatin formation
GO_0045892Biological processnegative regulation of DNA-templated transcription
GO_0001939Cellular componentfemale pronucleus
GO_0000775Cellular componentchromosome, centromeric region
GO_0010369Cellular componentchromocenter
GO_0000792Cellular componentheterochromatin
GO_0005654Cellular componentnucleoplasm
GO_0090734Cellular componentsite of DNA damage
GO_0016604Cellular componentnuclear body
GO_0005721Cellular componentpericentric heterochromatin
GO_0043231Cellular componentintracellular membrane-bounded organelle
GO_0001940Cellular componentmale pronucleus
GO_0000781Cellular componentchromosome, telomeric region
GO_0000785Cellular componentchromatin
GO_0005819Cellular componentspindle
GO_0005634Cellular componentnucleus
GO_0035064Molecular functionmethylated histone binding
GO_0019899Molecular functionenzyme binding
GO_0003682Molecular functionchromatin binding
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding
GO_1990226Molecular functionhistone methyltransferase binding

IV. Literature review

[source]
Gene nameCBX1
Protein nameCBX1 protein (Chromobox homolog 1 (HP1 beta homolog Drosophila ), isoform CRA_a) (cDNA, FLJ92997, Homo sapiens chromobox homolog 1 (HP1 beta homolog Drosophila ) (CBX1), mRNA)
Heterochromatin-specific nonhistone protein
Chromobox 1
Chromobox protein homolog 1 (HP1Hsbeta) (Heterochromatin protein 1 homolog beta) (HP1 beta) (Heterochromatin protein p25) (M31) (Modifier 1 protein) (p25beta)
SynonymshCG_2000655
CBX
DescriptionFUNCTION: Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane. .

AccessionsENST00000444685.1
P83916
ENST00000495350.5
Q9Y654
C9JWS9
ENST00000225603.9
J3KS05
B5MD17
ENST00000402583.5
Q6IBN6
ENST00000393408.7
K7ELA4
ENST00000581003.5