Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 11 studies | 25% ± 9% | |
| smooth muscle cell | 11 studies | 26% ± 8% | |
| fibroblast | 10 studies | 33% ± 6% | |
| connective tissue cell | 10 studies | 36% ± 15% | |
| myofibroblast cell | 7 studies | 34% ± 8% | |
| macrophage | 7 studies | 20% ± 7% | |
| neuron | 7 studies | 38% ± 21% | |
| pericyte | 7 studies | 27% ± 6% | |
| epithelial cell | 6 studies | 34% ± 14% | |
| abnormal cell | 5 studies | 26% ± 7% | |
| mesothelial cell | 5 studies | 34% ± 13% | |
| GABAergic neuron | 5 studies | 31% ± 10% | |
| glutamatergic neuron | 5 studies | 39% ± 11% | |
| interneuron | 5 studies | 35% ± 15% | |
| basal cell | 4 studies | 25% ± 11% | |
| astrocyte | 4 studies | 23% ± 11% | |
| oligodendrocyte precursor cell | 4 studies | 28% ± 9% | |
| hematopoietic precursor cell | 3 studies | 23% ± 3% | |
| progenitor cell | 3 studies | 29% ± 12% | |
| neural crest cell | 3 studies | 46% ± 16% | |
| amacrine cell | 3 studies | 42% ± 16% | |
| retina horizontal cell | 3 studies | 33% ± 15% | |
| retinal cone cell | 3 studies | 33% ± 15% | |
| ciliated cell | 3 studies | 32% ± 6% | |
| Mueller cell | 3 studies | 26% ± 7% | |
| dendritic cell | 3 studies | 26% ± 6% | |
| megakaryocyte-erythroid progenitor cell | 3 studies | 26% ± 10% | |
| natural killer cell | 3 studies | 18% ± 1% | |
| oligodendrocyte | 3 studies | 21% ± 2% | |
| CD4-positive, alpha-beta T cell | 3 studies | 21% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| brain | 100% | 5563.28 | 2642 / 2642 | 100% | 156.25 | 705 / 705 |
| breast | 100% | 3124.86 | 459 / 459 | 100% | 137.30 | 1117 / 1118 |
| ovary | 100% | 5721.46 | 180 / 180 | 100% | 67.16 | 428 / 430 |
| prostate | 100% | 3346.42 | 245 / 245 | 99% | 76.80 | 499 / 502 |
| lung | 100% | 2565.51 | 576 / 578 | 99% | 99.02 | 1148 / 1155 |
| thymus | 100% | 3500.46 | 653 / 653 | 99% | 83.05 | 599 / 605 |
| uterus | 100% | 5604.04 | 170 / 170 | 99% | 127.32 | 454 / 459 |
| bladder | 100% | 3678.29 | 21 / 21 | 99% | 87.70 | 498 / 504 |
| skin | 100% | 3492.86 | 1805 / 1809 | 98% | 88.38 | 463 / 472 |
| kidney | 100% | 2642.64 | 89 / 89 | 97% | 61.85 | 872 / 901 |
| intestine | 100% | 3404.40 | 966 / 966 | 97% | 59.20 | 510 / 527 |
| esophagus | 100% | 3336.93 | 1445 / 1445 | 96% | 57.96 | 175 / 183 |
| stomach | 99% | 2214.26 | 354 / 359 | 97% | 54.05 | 277 / 286 |
| adrenal gland | 100% | 2621.48 | 258 / 258 | 95% | 74.11 | 219 / 230 |
| pancreas | 92% | 1210.82 | 302 / 328 | 98% | 60.75 | 175 / 178 |
| liver | 73% | 700.45 | 165 / 226 | 73% | 32.00 | 297 / 406 |
| blood vessel | 100% | 3985.33 | 1335 / 1335 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 76.26 | 29 / 29 |
| spleen | 100% | 2323.76 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 93.16 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 44.52 | 1 / 1 |
| adipose | 100% | 2679.21 | 1202 / 1204 | 0% | 0 | 0 / 0 |
| muscle | 100% | 2748.86 | 801 / 803 | 0% | 0 | 0 / 0 |
| heart | 95% | 1974.42 | 814 / 861 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 85% | 35.70 | 68 / 80 |
| peripheral blood | 83% | 2238.15 | 770 / 929 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006974 | Biological process | DNA damage response |
| GO_0031507 | Biological process | heterochromatin formation |
| GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
| GO_0001939 | Cellular component | female pronucleus |
| GO_0000775 | Cellular component | chromosome, centromeric region |
| GO_0010369 | Cellular component | chromocenter |
| GO_0000792 | Cellular component | heterochromatin |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0090734 | Cellular component | site of DNA damage |
| GO_0016604 | Cellular component | nuclear body |
| GO_0005721 | Cellular component | pericentric heterochromatin |
| GO_0043231 | Cellular component | intracellular membrane-bounded organelle |
| GO_0001940 | Cellular component | male pronucleus |
| GO_0000781 | Cellular component | chromosome, telomeric region |
| GO_0000785 | Cellular component | chromatin |
| GO_0005819 | Cellular component | spindle |
| GO_0005634 | Cellular component | nucleus |
| GO_0035064 | Molecular function | methylated histone binding |
| GO_0019899 | Molecular function | enzyme binding |
| GO_0003682 | Molecular function | chromatin binding |
| GO_0042802 | Molecular function | identical protein binding |
| GO_0005515 | Molecular function | protein binding |
| GO_1990226 | Molecular function | histone methyltransferase binding |
| Gene name | CBX1 |
| Protein name | CBX1 protein (Chromobox homolog 1 (HP1 beta homolog Drosophila ), isoform CRA_a) (cDNA, FLJ92997, Homo sapiens chromobox homolog 1 (HP1 beta homolog Drosophila ) (CBX1), mRNA) Heterochromatin-specific nonhistone protein Chromobox 1 Chromobox protein homolog 1 (HP1Hsbeta) (Heterochromatin protein 1 homolog beta) (HP1 beta) (Heterochromatin protein p25) (M31) (Modifier 1 protein) (p25beta) |
| Synonyms | hCG_2000655 CBX |
| Description | FUNCTION: Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane. . |
| Accessions | ENST00000444685.1 P83916 ENST00000495350.5 Q9Y654 C9JWS9 ENST00000225603.9 J3KS05 B5MD17 ENST00000402583.5 Q6IBN6 ENST00000393408.7 K7ELA4 ENST00000581003.5 |