Biological process

GO:0006342, GO:0006343, GO:0016440, GO:0070869, GO:1904497

chromatin silencing, chromatin-mediated silencing, establishment of heterochromatin architecture, heterochromatin assembly

An epigenetic gene silencing mechanism in which chromatin is compacted into heterochromatin, resulting in a chromatin conformation refractory to transcription. This process starts with heterochromatin nucleation, its spreading, and ends with heterochromatin boundary formation.

establishment of chromatin silencing, establishment of heterochromatic silencing, heterochromatic silencing, heterochromatin assembly involved in chromatin silencing, heterochromatin formation involved in chromatin silencing, transcriptional gene silencing