Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| retinal cone cell | 4 studies | 52% ± 25% | |
| squamous epithelial cell | 3 studies | 35% ± 18% | |
| natural killer cell | 3 studies | 28% ± 8% | |
| neuron | 3 studies | 33% ± 11% | |
| amacrine cell | 3 studies | 38% ± 2% | |
| retina horizontal cell | 3 studies | 22% ± 7% | |
| erythrocyte | 3 studies | 26% ± 10% |
Insufficient scRNA-seq data for expression of H2AC25 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| adrenal gland | 100% | 1186.49 | 258 / 258 | 0% | 0 | 0 / 0 |
| ovary | 100% | 462.38 | 180 / 180 | 0% | 0 | 0 / 0 |
| spleen | 100% | 450.48 | 241 / 241 | 0% | 0 | 0 / 0 |
| skin | 100% | 495.90 | 1805 / 1809 | 0% | 0 | 0 / 0 |
| brain | 98% | 827.16 | 2590 / 2642 | 0% | 0 | 0 / 0 |
| prostate | 97% | 409.11 | 237 / 245 | 0% | 0 | 0 / 0 |
| uterus | 96% | 289.38 | 164 / 170 | 0% | 0 | 0 / 0 |
| heart | 96% | 314.50 | 823 / 861 | 0% | 0 | 0 / 0 |
| bladder | 90% | 180.24 | 19 / 21 | 0% | 0 | 0 / 0 |
| peripheral blood | 88% | 295.20 | 818 / 929 | 0% | 0 | 0 / 0 |
| stomach | 87% | 157.65 | 314 / 359 | 0% | 0 | 0 / 0 |
| esophagus | 87% | 300.12 | 1253 / 1445 | 0% | 0 | 0 / 0 |
| intestine | 87% | 171.96 | 837 / 966 | 0% | 0 | 0 / 0 |
| breast | 85% | 259.88 | 390 / 459 | 0% | 0 | 0 / 0 |
| lung | 83% | 146.58 | 478 / 578 | 0% | 0 | 0 / 0 |
| kidney | 66% | 124.91 | 59 / 89 | 0% | 0 | 0 / 0 |
| adipose | 66% | 128.80 | 790 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 59% | 87.72 | 793 / 1335 | 0% | 0 | 0 / 0 |
| thymus | 45% | 58.08 | 293 / 653 | 0% | 0 | 0 / 0 |
| pancreas | 44% | 51.88 | 145 / 328 | 0% | 0 | 0 / 0 |
| liver | 4% | 4.31 | 8 / 226 | 0% | 0 | 0 / 0 |
| muscle | 2% | 3.09 | 20 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0070914 | Biological process | UV-damage excision repair |
| GO_0006337 | Biological process | nucleosome disassembly |
| GO_0031507 | Biological process | heterochromatin formation |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0000786 | Cellular component | nucleosome |
| GO_0005634 | Cellular component | nucleus |
| GO_0046982 | Molecular function | protein heterodimerization activity |
| GO_0003677 | Molecular function | DNA binding |
| GO_0031492 | Molecular function | nucleosomal DNA binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0030527 | Molecular function | structural constituent of chromatin |
| Gene name | H2AC25 |
| Protein name | Histone H2A type 3 (H2A-clustered histone 25) |
| Synonyms | H2AW HIST3H2A |
| Description | FUNCTION: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| Accessions | ENST00000366695.3 ENST00000689584.1 ENST00000691624.1 Q7L7L0 ENST00000645741.1 |
