I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| ciliated cell | 3 studies | 70% ± 13% | |
| epithelial cell | 3 studies | 39% ± 18% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| ciliated cell | 3 studies | 70% ± 13% | |
| epithelial cell | 3 studies | 39% ± 18% |
Insufficient scRNA-seq data for expression of H2AC18 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| ureter | 0% | 0 | 0 / 0 | 100% | 1.01 | 1 / 1 |
| ovary | 0% | 0 | 0 / 0 | 66% | 2.41 | 285 / 430 |
| esophagus | 0% | 0 | 0 / 0 | 54% | 1.50 | 99 / 183 |
| prostate | 0% | 0 | 0 / 0 | 34% | 2.55 | 171 / 502 |
| stomach | 0% | 0 | 0 / 0 | 27% | 0.67 | 78 / 286 |
| breast | 0% | 0 | 0 / 0 | 23% | 0.75 | 254 / 1118 |
| brain | 0% | 0 | 0 / 0 | 14% | 0.39 | 97 / 705 |
| lung | 0% | 0 | 0 / 0 | 13% | 0.41 | 146 / 1155 |
| intestine | 0% | 0 | 0 / 0 | 10% | 0.25 | 52 / 527 |
| lymph node | 0% | 0 | 0 / 0 | 7% | 0.08 | 2 / 29 |
| uterus | 0% | 0 | 0 / 0 | 5% | 0.11 | 25 / 459 |
| bladder | 0% | 0 | 0 / 0 | 5% | 0.14 | 25 / 504 |
| tonsil | 0% | 0 | 0 / 0 | 4% | 0.05 | 2 / 45 |
| liver | 0% | 0 | 0 / 0 | 4% | 0.13 | 18 / 406 |
| kidney | 0% | 0 | 0 / 0 | 3% | 0.04 | 25 / 901 |
| skin | 0% | 0 | 0 / 0 | 2% | 0.04 | 11 / 472 |
| pancreas | 0% | 0 | 0 / 0 | 2% | 0.68 | 4 / 178 |
| thymus | 0% | 0 | 0 / 0 | 1% | 0.02 | 8 / 605 |
| adrenal gland | 0% | 0 | 0 / 0 | 0% | 0.01 | 1 / 230 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| adipose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| blood vessel | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| heart | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| muscle | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| peripheral blood | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spleen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0008150 | Biological process | biological_process |
| GO_0031507 | Biological process | heterochromatin formation |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0000786 | Cellular component | nucleosome |
| GO_0005634 | Cellular component | nucleus |
| GO_0046982 | Molecular function | protein heterodimerization activity |
| GO_0031492 | Molecular function | nucleosomal DNA binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0030527 | Molecular function | structural constituent of chromatin |
| GO_0003674 | Molecular function | molecular_function |
| Gene name | H2AC18 |
| Protein name | Histone H2A type 2-A (H2A-clustered histone 18) (H2A-clustered histone 19) (Histone H2A.2) (Histone H2A/o) |
| Synonyms | HIST2H2AA4 H2AC19 HIST2H2AA HIST2H2AA3; H2AFO |
| Description | FUNCTION: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| Accessions | Q6FI13 ENST00000369159.3 ENST00000607355.3 |
