Insufficient scRNA-seq data for expression of TNP1 at single-cell level.
Insufficient scRNA-seq data for expression of TNP1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
thymus | 96% | 39.40 | 627 / 653 | 3% | 0.05 | 16 / 605 |
ovary | 72% | 8.67 | 130 / 180 | 1% | 0.04 | 3 / 430 |
liver | 67% | 10.46 | 151 / 226 | 5% | 7.59 | 22 / 406 |
uterus | 63% | 8.56 | 107 / 170 | 1% | 0.03 | 5 / 459 |
kidney | 63% | 10.15 | 56 / 89 | 0% | 0 | 0 / 901 |
prostate | 60% | 58.61 | 147 / 245 | 0% | 0 | 0 / 502 |
spleen | 58% | 5.53 | 140 / 241 | 0% | 0 | 0 / 0 |
adrenal gland | 57% | 8.40 | 148 / 258 | 0% | 0 | 0 / 230 |
stomach | 55% | 7.91 | 197 / 359 | 1% | 0.01 | 2 / 286 |
pancreas | 54% | 6.65 | 178 / 328 | 0% | 0 | 0 / 178 |
bladder | 52% | 6.00 | 11 / 21 | 0% | 0 | 0 / 504 |
esophagus | 52% | 14.07 | 745 / 1445 | 1% | 0.02 | 1 / 183 |
intestine | 52% | 11.53 | 503 / 966 | 0% | 0 | 0 / 527 |
breast | 46% | 40.19 | 209 / 459 | 0% | 0.01 | 5 / 1118 |
skin | 41% | 11.33 | 733 / 1809 | 4% | 0.16 | 18 / 472 |
lung | 42% | 6.84 | 244 / 578 | 1% | 0.09 | 12 / 1155 |
blood vessel | 41% | 6.54 | 541 / 1335 | 0% | 0 | 0 / 0 |
adipose | 39% | 9.47 | 469 / 1204 | 0% | 0 | 0 / 0 |
muscle | 35% | 16.55 | 283 / 803 | 0% | 0 | 0 / 0 |
heart | 35% | 4.07 | 300 / 861 | 0% | 0 | 0 / 0 |
brain | 31% | 3.17 | 825 / 2642 | 0% | 0.01 | 3 / 705 |
peripheral blood | 28% | 3.06 | 256 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006338 | Biological process | chromatin remodeling |
GO_0007290 | Biological process | spermatid nucleus elongation |
GO_0035092 | Biological process | sperm DNA condensation |
GO_0006337 | Biological process | nucleosome disassembly |
GO_0031507 | Biological process | heterochromatin formation |
GO_0000012 | Biological process | single strand break repair |
GO_0030317 | Biological process | flagellated sperm motility |
GO_0035041 | Biological process | sperm DNA decondensation |
GO_0007289 | Biological process | spermatid nucleus differentiation |
GO_0045892 | Biological process | negative regulation of DNA-templated transcription |
GO_0019953 | Biological process | sexual reproduction |
GO_0007286 | Biological process | spermatid development |
GO_0010954 | Biological process | positive regulation of protein processing |
GO_0001673 | Cellular component | male germ cell nucleus |
GO_0000786 | Cellular component | nucleosome |
GO_0005634 | Cellular component | nucleus |
GO_0003677 | Molecular function | DNA binding |
GO_0005515 | Molecular function | protein binding |
Gene name | TNP1 |
Protein name | Spermatid nuclear transition protein 1 (STP-1) (TP-1) Spermatid nuclear transition protein 1 |
Synonyms | hCG_16381 |
Description | FUNCTION: Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. . |
Accessions | ENST00000236979.2 Q4ZG82 P09430 |