I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| plasmablast | 3 studies | 25% ± 10% | |
| platelet | 3 studies | 16% ± 1% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| plasmablast | 3 studies | 25% ± 10% | |
| platelet | 3 studies | 16% ± 1% |
Insufficient scRNA-seq data for expression of H2AC11 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| prostate | 97% | 71.73 | 237 / 245 | 88% | 5.58 | 444 / 502 |
| intestine | 96% | 57.22 | 928 / 966 | 88% | 5.03 | 464 / 527 |
| esophagus | 93% | 39.85 | 1344 / 1445 | 90% | 4.98 | 165 / 183 |
| thymus | 93% | 32.98 | 607 / 653 | 85% | 2.67 | 512 / 605 |
| stomach | 87% | 31.36 | 313 / 359 | 90% | 4.04 | 256 / 286 |
| lung | 94% | 39.52 | 545 / 578 | 72% | 3.72 | 831 / 1155 |
| bladder | 76% | 18.29 | 16 / 21 | 84% | 7.91 | 424 / 504 |
| uterus | 65% | 13.98 | 110 / 170 | 91% | 6.43 | 419 / 459 |
| skin | 79% | 39.09 | 1434 / 1809 | 74% | 3.35 | 350 / 472 |
| ovary | 62% | 12.74 | 112 / 180 | 89% | 5.53 | 384 / 430 |
| adrenal gland | 87% | 28.45 | 224 / 258 | 63% | 2.04 | 146 / 230 |
| breast | 68% | 17.78 | 311 / 459 | 80% | 7.48 | 894 / 1118 |
| liver | 74% | 31.41 | 167 / 226 | 65% | 4.70 | 262 / 406 |
| brain | 55% | 14.29 | 1454 / 2642 | 54% | 2.00 | 379 / 705 |
| kidney | 51% | 12.08 | 45 / 89 | 50% | 1.88 | 448 / 901 |
| spleen | 100% | 95.43 | 241 / 241 | 0% | 0 | 0 / 0 |
| blood vessel | 99% | 47.87 | 1316 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 98% | 89.43 | 912 / 929 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 93% | 4.34 | 42 / 45 |
| lymph node | 0% | 0 | 0 / 0 | 93% | 3.50 | 27 / 29 |
| pancreas | 24% | 3.79 | 78 / 328 | 58% | 3.03 | 104 / 178 |
| heart | 75% | 17.15 | 643 / 861 | 0% | 0 | 0 / 0 |
| adipose | 67% | 16.37 | 810 / 1204 | 0% | 0 | 0 / 0 |
| muscle | 43% | 8.45 | 345 / 803 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 34% | 0.83 | 27 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0008150 | Biological process | biological_process |
| GO_0031507 | Biological process | heterochromatin formation |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0000786 | Cellular component | nucleosome |
| GO_0005634 | Cellular component | nucleus |
| GO_0046982 | Molecular function | protein heterodimerization activity |
| GO_0019899 | Molecular function | enzyme binding |
| GO_0031492 | Molecular function | nucleosomal DNA binding |
| GO_0005515 | Molecular function | protein binding |
| GO_0030527 | Molecular function | structural constituent of chromatin |
| Gene name | H2AC11 |
| Protein name | Histone H2A type 1 (H2A.1) (Histone H2A/ptl) |
| Synonyms | H2AFP H2AC16 H2AC17 H2AFD H2AFI HIST1H2AL; HIST1H2AK; H2AFN HIST1H2AG; H2AFC HIST1H2AM HIST1H2AI; H2AC15 H2AC13 |
| Description | FUNCTION: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| Accessions | ENST00000618958.2 ENST00000613174.2 ENST00000358739.5 ENST00000359611.4 ENST00000359193.4 P0C0S8 |
