H2AJ | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
fibroblast	36 studies	35% ± 14%	Explore
pericyte	28 studies	47% ± 15%	Explore
macrophage	26 studies	31% ± 10%	Explore
smooth muscle cell	23 studies	41% ± 17%	Explore
natural killer cell	22 studies	25% ± 8%	Explore
classical monocyte	22 studies	35% ± 15%	Explore
endothelial cell	20 studies	29% ± 10%	Explore
conventional dendritic cell	19 studies	28% ± 13%	Explore
ciliated cell	18 studies	63% ± 20%	Explore
epithelial cell	18 studies	50% ± 18%	Explore
basal cell	17 studies	37% ± 17%	Explore
monocyte	16 studies	33% ± 11%	Explore
T cell	15 studies	22% ± 6%	Explore
non-classical monocyte	15 studies	29% ± 14%	Explore
CD4-positive, alpha-beta T cell	15 studies	22% ± 6%	Explore
connective tissue cell	14 studies	29% ± 9%	Explore
regulatory T cell	14 studies	22% ± 5%	Explore
CD8-positive, alpha-beta T cell	12 studies	22% ± 6%	Explore
myofibroblast cell	12 studies	34% ± 12%	Explore
secretory cell	11 studies	45% ± 18%	Explore
myeloid cell	10 studies	37% ± 19%	Explore
dendritic cell	9 studies	31% ± 18%	Explore
endothelial cell of lymphatic vessel	9 studies	19% ± 7%	Explore
platelet	9 studies	32% ± 11%	Explore
capillary endothelial cell	9 studies	21% ± 8%	Explore
gamma-delta T cell	9 studies	28% ± 16%	Explore
CD16-negative, CD56-bright natural killer cell, human	8 studies	31% ± 8%	Explore
CD16-positive, CD56-dim natural killer cell, human	8 studies	24% ± 5%	Explore
progenitor cell	8 studies	31% ± 14%	Explore
type I pneumocyte	7 studies	31% ± 9%	Explore
CD8-positive, alpha-beta memory T cell	7 studies	25% ± 7%	Explore
club cell	7 studies	41% ± 3%	Explore
mature NK T cell	7 studies	20% ± 4%	Explore
abnormal cell	7 studies	33% ± 14%	Explore
endothelial cell of artery	7 studies	20% ± 3%	Explore
goblet cell	7 studies	38% ± 15%	Explore
alveolar macrophage	6 studies	30% ± 6%	Explore
mast cell	6 studies	24% ± 7%	Explore
respiratory goblet cell	6 studies	46% ± 21%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	24% ± 9%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	6 studies	21% ± 6%	Explore
leukocyte	6 studies	26% ± 7%	Explore
mesothelial cell	6 studies	39% ± 10%	Explore
endothelial cell of vascular tree	6 studies	27% ± 13%	Explore
CD4-positive, alpha-beta memory T cell	5 studies	24% ± 5%	Explore
ionocyte	5 studies	40% ± 17%	Explore
mononuclear phagocyte	5 studies	28% ± 16%	Explore
epithelial cell of proximal tubule	5 studies	26% ± 5%	Explore
enterocyte	5 studies	37% ± 9%	Explore
transit amplifying cell	5 studies	27% ± 10%	Explore
type II pneumocyte	5 studies	25% ± 11%	Explore
effector CD4-positive, alpha-beta T cell	5 studies	25% ± 7%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	22% ± 2%	Explore
plasmablast	4 studies	43% ± 18%	Explore
deuterosomal cell	4 studies	58% ± 18%	Explore
squamous epithelial cell	4 studies	63% ± 22%	Explore
plasmacytoid dendritic cell	4 studies	19% ± 3%	Explore
hematopoietic precursor cell	4 studies	32% ± 16%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	4 studies	18% ± 2%	Explore
kidney loop of Henle epithelial cell	4 studies	21% ± 4%	Explore
plasma cell	4 studies	32% ± 12%	Explore
vein endothelial cell	4 studies	24% ± 8%	Explore
adventitial cell	4 studies	39% ± 4%	Explore
mucus secreting cell	4 studies	31% ± 8%	Explore
intermediate monocyte	4 studies	39% ± 17%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	68% ± 8%	Explore
luminal cell of prostate epithelium	4 studies	66% ± 19%	Explore
erythrocyte	4 studies	40% ± 24%	Explore
brush cell	4 studies	38% ± 13%	Explore
enteroendocrine cell	4 studies	32% ± 16%	Explore
mucosal invariant T cell	4 studies	18% ± 2%	Explore
duct epithelial cell	3 studies	46% ± 13%	Explore
pancreatic A cell	3 studies	69% ± 10%	Explore
type B pancreatic cell	3 studies	44% ± 11%	Explore
exhausted T cell	3 studies	33% ± 16%	Explore
glomerular endothelial cell	3 studies	24% ± 4%	Explore
podocyte	3 studies	39% ± 16%	Explore
renal alpha-intercalated cell	3 studies	35% ± 7%	Explore
lymphocyte	3 studies	30% ± 7%	Explore
megakaryocyte	3 studies	41% ± 8%	Explore
precursor B cell	3 studies	34% ± 10%	Explore
pro-B cell	3 studies	25% ± 6%	Explore
serous secreting cell	3 studies	42% ± 0%	Explore
T follicular helper cell	3 studies	21% ± 4%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	25% ± 3%	Explore
innate lymphoid cell	3 studies	23% ± 2%	Explore
B cell	3 studies	23% ± 7%	Explore
adipocyte	3 studies	21% ± 4%	Explore
inflammatory macrophage	3 studies	27% ± 9%	Explore
hematopoietic stem cell	3 studies	29% ± 12%	Explore
glial cell	3 studies	24% ± 5%	Explore
group 3 innate lymphoid cell	3 studies	37% ± 14%	Explore
double negative thymocyte	3 studies	30% ± 17%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	14 studies	37% ± 14%	Explore
peripheral blood	12 studies	24% ± 8%	Explore
intestine	9 studies	28% ± 11%	Explore
kidney	7 studies	25% ± 7%	Explore
prostate	5 studies	33% ± 12%	Explore
uterus	4 studies	33% ± 18%	Explore
breast	4 studies	31% ± 3%	Explore
liver	4 studies	34% ± 27%	Explore
pancreas	3 studies	55% ± 10%	Explore
bone marrow	3 studies	23% ± 7%	Explore
eye	3 studies	25% ± 10%	Explore
placenta	3 studies	25% ± 6%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	100%	8125.76	245 / 245	100%	509.09	501 / 502
pancreas	99%	2828.38	326 / 328	98%	72.30	175 / 178
thymus	100%	2847.42	650 / 653	98%	61.11	593 / 605
breast	100%	6395.81	459 / 459	97%	156.15	1089 / 1118
kidney	100%	2976.38	89 / 89	97%	55.88	871 / 901
bladder	100%	3951.14	21 / 21	96%	105.87	485 / 504
intestine	100%	3339.89	966 / 966	93%	75.44	489 / 527
esophagus	100%	3479.74	1445 / 1445	91%	38.79	166 / 183
stomach	99%	2659.77	357 / 359	90%	66.24	258 / 286
uterus	100%	3607.10	170 / 170	89%	55.23	410 / 459
lung	100%	4109.75	576 / 578	88%	42.21	1021 / 1155
skin	100%	4657.03	1809 / 1809	87%	79.69	412 / 472
adrenal gland	100%	4668.79	258 / 258	75%	59.40	172 / 230
ovary	97%	2042.10	174 / 180	77%	34.27	332 / 430
liver	63%	900.57	143 / 226	94%	57.94	383 / 406
adipose	100%	6463.15	1204 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	100%	95.20	80 / 80
spleen	100%	2973.85	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	322.61	1 / 1
blood vessel	100%	8291.25	1334 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	97%	48.08	28 / 29
heart	93%	2032.09	797 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	84%	38.58	38 / 45
muscle	83%	1348.00	666 / 803	0%	0	0 / 0
peripheral blood	80%	1225.90	743 / 929	0%	0	0 / 0
brain	46%	661.30	1218 / 2642	19%	5.35	137 / 705
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0008150	Biological process	biological_process
GO_0031507	Biological process	heterochromatin formation
GO_0070062	Cellular component	extracellular exosome
GO_0000786	Cellular component	nucleosome
GO_0005634	Cellular component	nucleus
GO_0046982	Molecular function	protein heterodimerization activity
GO_0031492	Molecular function	nucleosomal DNA binding
GO_0030527	Molecular function	structural constituent of chromatin
GO_0003674	Molecular function	molecular_function

IV. Literature review

[source]

Gene name	H2AJ
Protein name	Histone H2A Histone H2A.J (H2a/j)
Synonyms	H2AFJ
Description	FUNCTION: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Accessions	H0YFX9 ENST00000544848.3 [Q9BTM1-1] ENST00000389078.3 [Q9BTM1-1] ENST00000501744.2 Q9BTM1

H2AJ report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review