Name | Number of supported studies | Average coverage | |
---|---|---|---|
neuron | 7 studies | 44% ± 19% | |
connective tissue cell | 5 studies | 40% ± 14% | |
oligodendrocyte precursor cell | 5 studies | 24% ± 6% | |
progenitor cell | 4 studies | 20% ± 3% | |
epithelial cell | 4 studies | 36% ± 15% | |
myofibroblast cell | 4 studies | 18% ± 2% | |
adipocyte | 4 studies | 30% ± 8% | |
GABAergic neuron | 4 studies | 35% ± 6% | |
glutamatergic neuron | 4 studies | 39% ± 8% | |
fibroblast | 3 studies | 20% ± 5% | |
smooth muscle cell | 3 studies | 22% ± 2% | |
ciliated cell | 3 studies | 21% ± 1% | |
basal cell | 3 studies | 29% ± 9% | |
astrocyte | 3 studies | 20% ± 1% | |
interneuron | 3 studies | 33% ± 13% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 5 studies | 25% ± 8% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
thymus | 100% | 759.24 | 653 / 653 | 99% | 7.46 | 597 / 605 |
ovary | 100% | 1196.65 | 180 / 180 | 95% | 10.46 | 407 / 430 |
prostate | 100% | 1145.05 | 245 / 245 | 93% | 8.66 | 469 / 502 |
uterus | 100% | 1408.02 | 170 / 170 | 90% | 11.72 | 413 / 459 |
pancreas | 98% | 409.09 | 320 / 328 | 90% | 5.93 | 161 / 178 |
bladder | 100% | 1098.29 | 21 / 21 | 87% | 9.14 | 440 / 504 |
brain | 99% | 739.74 | 2628 / 2642 | 79% | 7.42 | 557 / 705 |
breast | 96% | 536.99 | 441 / 459 | 78% | 7.10 | 877 / 1118 |
intestine | 100% | 893.49 | 966 / 966 | 69% | 4.72 | 361 / 527 |
lung | 98% | 480.40 | 569 / 578 | 70% | 5.58 | 807 / 1155 |
stomach | 100% | 593.17 | 359 / 359 | 62% | 4.27 | 178 / 286 |
kidney | 100% | 861.87 | 89 / 89 | 62% | 2.82 | 559 / 901 |
esophagus | 100% | 1057.49 | 1444 / 1445 | 60% | 4.75 | 109 / 183 |
adrenal gland | 61% | 138.17 | 158 / 258 | 82% | 5.65 | 189 / 230 |
liver | 77% | 251.30 | 173 / 226 | 58% | 4.33 | 236 / 406 |
skin | 100% | 704.27 | 1802 / 1809 | 23% | 1.38 | 107 / 472 |
ureter | 0% | 0 | 0 / 0 | 100% | 3.25 | 1 / 1 |
blood vessel | 98% | 374.61 | 1302 / 1335 | 0% | 0 | 0 / 0 |
heart | 96% | 646.98 | 828 / 861 | 0% | 0 | 0 / 0 |
spleen | 93% | 223.37 | 224 / 241 | 0% | 0 | 0 / 0 |
muscle | 90% | 320.56 | 723 / 803 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 87% | 8.69 | 39 / 45 |
adipose | 81% | 230.54 | 975 / 1204 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 54% | 2.20 | 43 / 80 |
lymph node | 0% | 0 | 0 / 0 | 38% | 1.01 | 11 / 29 |
peripheral blood | 12% | 22.05 | 115 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0045814 | Biological process | negative regulation of gene expression, epigenetic |
GO_0007549 | Biological process | sex-chromosome dosage compensation |
GO_0071169 | Biological process | establishment of protein localization to chromatin |
GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
GO_0031507 | Biological process | heterochromatin formation |
GO_0006334 | Biological process | nucleosome assembly |
GO_1901837 | Biological process | negative regulation of transcription of nucleolar large rRNA by RNA polymerase I |
GO_0007420 | Biological process | brain development |
GO_0045618 | Biological process | positive regulation of keratinocyte differentiation |
GO_0000786 | Cellular component | nucleosome |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005654 | Cellular component | nucleoplasm |
GO_0001740 | Cellular component | Barr body |
GO_0000781 | Cellular component | chromosome, telomeric region |
GO_0000785 | Cellular component | chromatin |
GO_0005634 | Cellular component | nucleus |
GO_0000977 | Molecular function | RNA polymerase II transcription regulatory region sequence-specific DNA binding |
GO_0000976 | Molecular function | transcription cis-regulatory region binding |
GO_0031492 | Molecular function | nucleosomal DNA binding |
GO_0030527 | Molecular function | structural constituent of chromatin |
GO_0046982 | Molecular function | protein heterodimerization activity |
GO_0031490 | Molecular function | chromatin DNA binding |
GO_0005515 | Molecular function | protein binding |
Gene name | MACROH2A2 |
Protein name | Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2) Histone H2A MacroH2A.2 histone |
Synonyms | H2AFY2 |
Description | FUNCTION: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in stable X chromosome inactivation. . |
Accessions | A0A7I2V412 ENST00000676609.1 A0A7I2V4W8 ENST00000677373.1 ENST00000676608.1 ENST00000676896.1 A0A7I2V423 Q9P0M6 A0A7I2V3Z8 Q5SQT3 ENST00000678195.1 A0A7I2V3R0 ENST00000678931.1 ENST00000679349.1 A0A7I2V2N7 ENST00000678523.1 ENST00000676699.1 A0A7I2YQR8 ENST00000678526.1 A0A7I2YQD6 A0A7I2V522 A0A7I2V3M7 ENST00000678762.1 A0A7I2V583 ENST00000678191.1 A0A7I2V3B3 A0A7I2V3C2 ENST00000679292.1 A0A7I2V633 A0A7I2V5G0 ENST00000677894.1 ENST00000373255.9 A0A7I2V5A9 ENST00000678586.1 ENST00000678682.1 ENST00000455786.1 ENST00000677954.1 ENST00000677557.1 A0A7I2V6E9 A0A7I2V4D9 A0A7I2YQF0 ENST00000676692.1 ENST00000678425.1 ENST00000678503.1 ENST00000677881.1 A0A7I2YQB9 |