H2AC7 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of H2AC7 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of H2AC7 at tissue level.

III. Associated gene sets

GO_0008150Biological processbiological_process
GO_0031507Biological processheterochromatin formation
GO_0070062Cellular componentextracellular exosome
GO_0000786Cellular componentnucleosome
GO_0005634Cellular componentnucleus
GO_0046982Molecular functionprotein heterodimerization activity
GO_0031492Molecular functionnucleosomal DNA binding
GO_0030527Molecular functionstructural constituent of chromatin
GO_0003674Molecular functionmolecular_function

IV. Literature review

[source]
Gene nameH2AC7
Protein nameHistone H2A type 1-D (Histone H2A.3) (Histone H2A/g)
SynonymsHIST1H2AD
H2AFG
DescriptionFUNCTION: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

AccessionsENST00000341023.2
P20671