Insufficient scRNA-seq data for expression of H4C1 at single-cell level.
Insufficient scRNA-seq data for expression of H4C1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
stomach | 0% | 0 | 0 / 0 | 20% | 1.40 | 58 / 286 |
ovary | 0% | 0 | 0 / 0 | 18% | 0.45 | 78 / 430 |
intestine | 0% | 0 | 0 / 0 | 17% | 1.10 | 89 / 527 |
esophagus | 0% | 0 | 0 / 0 | 15% | 0.25 | 27 / 183 |
bladder | 0% | 0 | 0 / 0 | 11% | 2.87 | 54 / 504 |
lymph node | 0% | 0 | 0 / 0 | 10% | 0.26 | 3 / 29 |
uterus | 0% | 0 | 0 / 0 | 9% | 0.83 | 43 / 459 |
lung | 0% | 0 | 0 / 0 | 8% | 1.02 | 87 / 1155 |
brain | 0% | 0 | 0 / 0 | 8% | 0.34 | 53 / 705 |
thymus | 0% | 0 | 0 / 0 | 7% | 0.19 | 45 / 605 |
adrenal gland | 0% | 0 | 0 / 0 | 7% | 0.13 | 17 / 230 |
tonsil | 0% | 0 | 0 / 0 | 7% | 0.10 | 3 / 45 |
breast | 0% | 0 | 0 / 0 | 4% | 1.11 | 50 / 1118 |
pancreas | 0% | 0 | 0 / 0 | 2% | 0.55 | 4 / 178 |
prostate | 0% | 0 | 0 / 0 | 2% | 0.08 | 9 / 502 |
kidney | 0% | 0 | 0 / 0 | 2% | 0.18 | 14 / 901 |
skin | 0% | 0 | 0 / 0 | 1% | 0.01 | 5 / 472 |
liver | 0% | 0 | 0 / 0 | 1% | 0.02 | 4 / 406 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
adipose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
blood vessel | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
heart | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
muscle | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
peripheral blood | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spleen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006325 | Biological process | chromatin organization |
GO_0006334 | Biological process | nucleosome assembly |
GO_0061644 | Biological process | protein localization to CENP-A containing chromatin |
GO_0045653 | Biological process | negative regulation of megakaryocyte differentiation |
GO_0032200 | Biological process | telomere organization |
GO_0005576 | Cellular component | extracellular region |
GO_0000786 | Cellular component | nucleosome |
GO_0016020 | Cellular component | membrane |
GO_0070062 | Cellular component | extracellular exosome |
GO_0032991 | Cellular component | protein-containing complex |
GO_0005654 | Cellular component | nucleoplasm |
GO_0043505 | Cellular component | CENP-A containing nucleosome |
GO_0000781 | Cellular component | chromosome, telomeric region |
GO_0005634 | Cellular component | nucleus |
GO_0003677 | Molecular function | DNA binding |
GO_0030527 | Molecular function | structural constituent of chromatin |
GO_0003723 | Molecular function | RNA binding |
GO_0046982 | Molecular function | protein heterodimerization activity |
GO_0005515 | Molecular function | protein binding |
Gene name | H4C1 |
Protein name | Histone H4 |
Synonyms | H4/C HIST1H4B; H4/E H4/O HIST2H4A; H4C16 H4FH HIST1H4K; H4C13 HIST1H4L; H4FC H4/J HIST1H4A; H4FE H4/I H4C8 H4/M H4/D H4/H H4C11 HIST1H4I; H4C9 H4C15 H4FO H4C4 H4C5 H4FM H4/K H4C2 H4FB H4/A HIST1H4J; H4C14 HIST1H4D; HIST1H4C; H4FG H4FJ H4C6 H4FI HIST1H4E; H4F2 H4FK H4/G H4-16 HIST2H4B; HIST2H4 HIST1H4H; H4FA H4FD HIST1H4F; H4/N H4/B H4FN HIST4H4 H4C12 H4C3 |
Description | FUNCTION: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
Accessions | ENST00000578186.3 ENST00000615164.3 ENST00000634956.1 ENST00000618193.1 ENST00000377727.2 ENST00000377745.5 ENST00000579512.3 ENST00000615353.2 ENST00000618305.2 ENST00000617569.2 ENST00000612061.1 ENST00000355057.3 ENST00000539745.2 ENST00000244537.6 ENST00000614272.1 ENST00000614247.2 ENST00000621520.1 P62805 ENST00000358064.3 ENST00000613412.1 ENST00000634560.1 ENST00000611927.2 ENST00000377803.4 |