H4C1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of H4C1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of H4C1 at tissue level.

III. Associated gene sets

GO_0006325Biological processchromatin organization
GO_0006334Biological processnucleosome assembly
GO_0061644Biological processprotein localization to CENP-A containing chromatin
GO_0045653Biological processnegative regulation of megakaryocyte differentiation
GO_0032200Biological processtelomere organization
GO_0005576Cellular componentextracellular region
GO_0000786Cellular componentnucleosome
GO_0016020Cellular componentmembrane
GO_0070062Cellular componentextracellular exosome
GO_0032991Cellular componentprotein-containing complex
GO_0005654Cellular componentnucleoplasm
GO_0043505Cellular componentCENP-A containing nucleosome
GO_0000781Cellular componentchromosome, telomeric region
GO_0005634Cellular componentnucleus
GO_0003677Molecular functionDNA binding
GO_0030527Molecular functionstructural constituent of chromatin
GO_0003723Molecular functionRNA binding
GO_0046982Molecular functionprotein heterodimerization activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameH4C1
Protein nameHistone H4
SynonymsH4/C
HIST1H4B;
H4/E
H4/O
HIST2H4A;
H4C16
H4FH
HIST1H4K;
H4C13
HIST1H4L;
H4FC
H4/J
HIST1H4A;
H4FE
H4/I
H4C8
H4/M
H4/D
H4/H
H4C11
HIST1H4I;
H4C9
H4C15
H4FO
H4C4
H4C5
H4FM
H4/K
H4C2
H4FB
H4/A
HIST1H4J;
H4C14
HIST1H4D;
HIST1H4C;
H4FG
H4FJ
H4C6
H4FI
HIST1H4E;
H4F2
H4FK
H4/G
H4-16
HIST2H4B;
HIST2H4
HIST1H4H;
H4FA
H4FD
HIST1H4F;
H4/N
H4/B
H4FN
HIST4H4
H4C12
H4C3
DescriptionFUNCTION: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

AccessionsENST00000578186.3
ENST00000615164.3
ENST00000634956.1
ENST00000618193.1
ENST00000377727.2
ENST00000377745.5
ENST00000579512.3
ENST00000615353.2
ENST00000618305.2
ENST00000617569.2
ENST00000612061.1
ENST00000355057.3
ENST00000539745.2
ENST00000244537.6
ENST00000614272.1
ENST00000614247.2
ENST00000621520.1
P62805
ENST00000358064.3
ENST00000613412.1
ENST00000634560.1
ENST00000611927.2
ENST00000377803.4