H3-4 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of H3-4 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
bladder	86%	4.10	18 / 21	3%	0.06	16 / 504
ovary	78%	2.82	141 / 180	10%	0.15	44 / 430
esophagus	65%	2.01	937 / 1445	21%	0.35	38 / 183
uterus	83%	3.30	141 / 170	1%	0.04	6 / 459
intestine	70%	2.33	679 / 966	5%	0.07	24 / 527
prostate	70%	2.31	172 / 245	0%	0.01	1 / 502
skin	69%	2.25	1254 / 1809	1%	0.01	3 / 472
blood vessel	65%	1.99	863 / 1335	0%	0	0 / 0
breast	60%	1.91	275 / 459	3%	0.10	38 / 1118
thymus	61%	1.67	396 / 653	0%	0	0 / 605
spleen	60%	1.56	145 / 241	0%	0	0 / 0
lung	55%	1.43	320 / 578	4%	0.07	45 / 1155
adrenal gland	57%	1.49	147 / 258	0%	0	0 / 230
adipose	55%	1.54	665 / 1204	0%	0	0 / 0
stomach	48%	1.26	174 / 359	6%	0.11	17 / 286
heart	47%	1.07	404 / 861	0%	0	0 / 0
muscle	42%	0.78	335 / 803	0%	0	0 / 0
brain	39%	1.18	1027 / 2642	1%	0.02	6 / 705
kidney	37%	1.02	33 / 89	1%	0.02	9 / 901
peripheral blood	38%	0.96	352 / 929	0%	0	0 / 0
pancreas	32%	0.59	104 / 328	2%	0.05	4 / 178
liver	13%	0.23	29 / 226	1%	0.01	4 / 406
tonsil	0%	0	0 / 0	2%	0.03	1 / 45
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0006325	Biological process	chromatin organization
GO_0006334	Biological process	nucleosome assembly
GO_0070062	Cellular component	extracellular exosome
GO_0000781	Cellular component	chromosome, telomeric region
GO_0005654	Cellular component	nucleoplasm
GO_0000786	Cellular component	nucleosome
GO_0005634	Cellular component	nucleus
GO_0030527	Molecular function	structural constituent of chromatin
GO_0046982	Molecular function	protein heterodimerization activity
GO_0003677	Molecular function	DNA binding
GO_0005515	Molecular function	protein binding

Gene name	H3-4
Protein name	Histone H3.1t (H3/t) (H3t) (H3/g) (Histone H3.4)
Synonyms	H3FT HIST3H3
Description	FUNCTION: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Accessions	ENST00000644869.3 ENST00000366696.2 Q16695

H3-4 report