MTA2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of MTA2 at tissue level.

III. Associated gene sets

GO_0006325Biological processchromatin organization
GO_2000736Biological processregulation of stem cell differentiation
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0006338Biological processchromatin remodeling
GO_0042659Biological processregulation of cell fate specification
GO_0045893Biological processpositive regulation of DNA-templated transcription
GO_0010762Biological processregulation of fibroblast migration
GO_0045892Biological processnegative regulation of DNA-templated transcription
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0016020Cellular componentmembrane
GO_0032991Cellular componentprotein-containing complex
GO_0005654Cellular componentnucleoplasm
GO_0000118Cellular componenthistone deacetylase complex
GO_0016581Cellular componentNuRD complex
GO_0000781Cellular componentchromosome, telomeric region
GO_0000785Cellular componentchromatin
GO_0005667Cellular componenttranscription regulator complex
GO_0005634Cellular componentnucleus
GO_0043565Molecular functionsequence-specific DNA binding
GO_0004407Molecular functionhistone deacetylase activity
GO_0031492Molecular functionnucleosomal DNA binding
GO_0003714Molecular functiontranscription corepressor activity
GO_0061629Molecular functionRNA polymerase II-specific DNA-binding transcription factor binding
GO_0046872Molecular functionmetal ion binding
GO_0003713Molecular functiontranscription coactivator activity
GO_0005515Molecular functionprotein binding
GO_0042826Molecular functionhistone deacetylase binding

IV. Literature review

[source]
Gene nameMTA2
Protein nameMetastasis-associated protein MTA2 (Metastasis-associated 1-like 1) (MTA1-L1 protein) (p53 target protein in deacetylase complex)
SynonymsMTA1L1
PID
DescriptionFUNCTION: May function as a transcriptional coregulator . Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin . .

AccessionsO94776
ENST00000527204.5 [O94776-2]
ENST00000278823.7 [O94776-1]
ENST00000524902.5 [O94776-2]