NuRD complex

I. Literature review

[source]
NameNuRD complex
IDGO_0016581
collection_id

Cellular component

Exact synonym

NRD complex, nucleosome remodeling and histone deacetylation complex

Description

An approximately 2 MDa multi-subunit complex that exhibits ATP-dependent chromatin remodeling activity in addition to histone deacetylase (HDAC) activity, and has been shown to establish transcriptional repression of a number of target genes in vertebrates, invertebrates and fungi. Amongst its subunits, the NuRD complex contains histone deacetylases, histone binding proteins and Mi-2-like proteins.

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Genes