CDK2AP2 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
natural killer cell	32 studies	33% ± 10%	Explore
CD8-positive, alpha-beta T cell	26 studies	33% ± 17%	Explore
T cell	21 studies	27% ± 9%	Explore
CD4-positive, alpha-beta T cell	21 studies	27% ± 16%	Explore
mature NK T cell	19 studies	29% ± 8%	Explore
plasmacytoid dendritic cell	19 studies	50% ± 15%	Explore
B cell	18 studies	26% ± 9%	Explore
conventional dendritic cell	18 studies	32% ± 10%	Explore
regulatory T cell	17 studies	29% ± 11%	Explore
gamma-delta T cell	16 studies	31% ± 10%	Explore
non-classical monocyte	15 studies	29% ± 10%	Explore
plasma cell	15 studies	42% ± 16%	Explore
CD16-positive, CD56-dim natural killer cell, human	14 studies	34% ± 10%	Explore
macrophage	12 studies	23% ± 7%	Explore
epithelial cell	12 studies	40% ± 21%	Explore
memory B cell	11 studies	22% ± 6%	Explore
classical monocyte	11 studies	25% ± 7%	Explore
CD16-negative, CD56-bright natural killer cell, human	11 studies	33% ± 10%	Explore
plasmablast	10 studies	40% ± 23%	Explore
CD8-positive, alpha-beta memory T cell	10 studies	32% ± 14%	Explore
naive B cell	10 studies	20% ± 4%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	9 studies	25% ± 11%	Explore
mucosal invariant T cell	9 studies	25% ± 7%	Explore
endothelial cell	9 studies	26% ± 7%	Explore
effector memory CD8-positive, alpha-beta T cell	8 studies	26% ± 9%	Explore
monocyte	8 studies	22% ± 9%	Explore
abnormal cell	8 studies	31% ± 9%	Explore
dendritic cell	8 studies	46% ± 21%	Explore
type II pneumocyte	8 studies	35% ± 21%	Explore
CD4-positive, alpha-beta memory T cell	7 studies	35% ± 13%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	45% ± 22%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	7 studies	17% ± 2%	Explore
pericyte	7 studies	26% ± 10%	Explore
T follicular helper cell	7 studies	30% ± 10%	Explore
ciliated cell	7 studies	36% ± 11%	Explore
myeloid cell	6 studies	27% ± 9%	Explore
basal cell	6 studies	26% ± 11%	Explore
exhausted T cell	5 studies	45% ± 14%	Explore
kidney loop of Henle epithelial cell	5 studies	23% ± 7%	Explore
IgA plasma cell	5 studies	26% ± 7%	Explore
smooth muscle cell	5 studies	21% ± 5%	Explore
effector memory CD4-positive, alpha-beta T cell	5 studies	32% ± 16%	Explore
innate lymphoid cell	5 studies	30% ± 5%	Explore
goblet cell	5 studies	24% ± 7%	Explore
mast cell	5 studies	18% ± 4%	Explore
club cell	4 studies	31% ± 9%	Explore
deuterosomal cell	4 studies	46% ± 10%	Explore
secretory cell	4 studies	23% ± 11%	Explore
epithelial cell of proximal tubule	4 studies	22% ± 7%	Explore
IgG plasma cell	4 studies	22% ± 5%	Explore
transit amplifying cell	4 studies	25% ± 5%	Explore
enterocyte	4 studies	22% ± 4%	Explore
immature B cell	4 studies	22% ± 8%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	49% ± 13%	Explore
T-helper 17 cell	4 studies	34% ± 20%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	4 studies	30% ± 6%	Explore
respiratory goblet cell	3 studies	31% ± 17%	Explore
pancreatic A cell	3 studies	23% ± 5%	Explore
type B pancreatic cell	3 studies	34% ± 4%	Explore
leukocyte	3 studies	31% ± 12%	Explore
mononuclear phagocyte	3 studies	26% ± 14%	Explore
common myeloid progenitor	3 studies	23% ± 7%	Explore
precursor B cell	3 studies	31% ± 6%	Explore
type I pneumocyte	3 studies	39% ± 9%	Explore
retinal cone cell	3 studies	23% ± 4%	Explore
intraepithelial lymphocyte	3 studies	37% ± 7%	Explore
germinal center B cell	3 studies	36% ± 6%	Explore
intermediate monocyte	3 studies	34% ± 8%	Explore
intestinal crypt stem cell	3 studies	21% ± 7%	Explore
group 3 innate lymphoid cell	3 studies	33% ± 10%	Explore
T-helper 1 cell	3 studies	32% ± 14%	Explore
double negative thymocyte	3 studies	34% ± 11%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	21% ± 4%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	12 studies	25% ± 4%	Explore
lung	10 studies	23% ± 8%	Explore
intestine	6 studies	19% ± 4%	Explore
kidney	4 studies	28% ± 8%	Explore
brain	4 studies	19% ± 3%	Explore
pancreas	3 studies	30% ± 4%	Explore
lymph node	3 studies	32% ± 11%	Explore
liver	3 studies	22% ± 5%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	3478.98	1445 / 1445	100%	128.86	183 / 183
ovary	100%	1893.53	180 / 180	100%	207.54	430 / 430
thymus	100%	6327.16	653 / 653	100%	165.24	605 / 605
uterus	100%	2521.67	170 / 170	100%	145.85	459 / 459
liver	100%	4881.58	226 / 226	100%	113.32	405 / 406
brain	100%	2324.66	2633 / 2642	100%	80.86	705 / 705
intestine	100%	3104.77	966 / 966	99%	130.21	523 / 527
prostate	100%	3425.76	245 / 245	99%	125.50	498 / 502
kidney	100%	5834.10	89 / 89	99%	134.69	893 / 901
lung	100%	3619.88	578 / 578	98%	137.78	1136 / 1155
stomach	100%	2761.55	359 / 359	98%	141.64	281 / 286
bladder	100%	3079.00	21 / 21	98%	135.86	493 / 504
pancreas	100%	2876.08	328 / 328	98%	98.24	174 / 178
breast	100%	2522.34	459 / 459	98%	95.64	1092 / 1118
adrenal gland	100%	4523.75	258 / 258	95%	73.66	219 / 230
skin	95%	1288.35	1727 / 1809	98%	103.38	464 / 472
eye	0%	0	0 / 0	100%	82.52	80 / 80
lymph node	0%	0	0 / 0	100%	271.61	29 / 29
spleen	100%	3291.59	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	117.01	45 / 45
ureter	0%	0	0 / 0	100%	126.85	1 / 1
adipose	100%	2816.28	1203 / 1204	0%	0	0 / 0
blood vessel	100%	4817.06	1333 / 1335	0%	0	0 / 0
heart	99%	3510.71	856 / 861	0%	0	0 / 0
peripheral blood	99%	2719.34	917 / 929	0%	0	0 / 0
muscle	78%	871.30	625 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_2000134	Biological process	negative regulation of G1/S transition of mitotic cell cycle
GO_0070507	Biological process	regulation of microtubule cytoskeleton organization
GO_2000035	Biological process	regulation of stem cell division
GO_0016581	Cellular component	NuRD complex
GO_0005874	Cellular component	microtubule
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0005515	Molecular function	protein binding

IV. Literature review

[source]

Gene name	CDK2AP2
Protein name	Cyclin-dependent kinase 2-associated protein 2 (CDK2-associated protein 2) (DOC-1-related protein) (DOC-1R) Cyclin-dependent kinase 2-associated protein Cyclin dependent kinase 2 associated protein 2
Synonyms	DOC1R DOC-1R hCG_21052
Description	FUNCTION: Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin . Inhibits cell cycle G1/S phase transition by repressing CDK2 expression and activation; represses CDK2 activation by inhibiting its interaction with cyclin E and A . Plays a role in regulating the self-renewal of embryonic stem cells (ESCs) and in maintaining cell survival during terminal differentiation of ESCs (By similarity). Regulates microtubule organization of metaphase II oocytes (By similarity). .
Accessions	ENST00000301488.8 ENST00000531178.1 E9PQJ3 O75956 E9PKR4 Q6IAV4 ENST00000531506.1

CDK2AP2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review