Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| endothelial cell | 9 studies | 28% ± 10% | |
| adipocyte | 8 studies | 25% ± 6% | |
| glutamatergic neuron | 7 studies | 42% ± 24% | |
| GABAergic neuron | 7 studies | 39% ± 21% | |
| oligodendrocyte | 7 studies | 27% ± 7% | |
| epithelial cell | 5 studies | 28% ± 12% | |
| endothelial cell of lymphatic vessel | 5 studies | 22% ± 6% | |
| astrocyte | 5 studies | 29% ± 7% | |
| microglial cell | 4 studies | 21% ± 4% | |
| cardiac muscle cell | 4 studies | 25% ± 2% | |
| oligodendrocyte precursor cell | 4 studies | 34% ± 9% | |
| fibroblast | 4 studies | 20% ± 7% | |
| type I pneumocyte | 4 studies | 20% ± 5% | |
| type II pneumocyte | 4 studies | 21% ± 6% | |
| interneuron | 4 studies | 47% ± 21% | |
| neuron | 3 studies | 29% ± 11% | |
| GABAergic interneuron | 3 studies | 17% ± 1% | |
| amacrine cell | 3 studies | 22% ± 3% | |
| hepatocyte | 3 studies | 35% ± 19% | |
| macrophage | 3 studies | 21% ± 3% | |
| transit amplifying cell | 3 studies | 36% ± 25% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 1355.33 | 1445 / 1445 | 100% | 18.72 | 183 / 183 |
| lung | 100% | 1396.43 | 578 / 578 | 100% | 17.60 | 1155 / 1155 |
| breast | 100% | 1879.05 | 459 / 459 | 100% | 18.07 | 1117 / 1118 |
| intestine | 100% | 1508.10 | 966 / 966 | 100% | 18.67 | 526 / 527 |
| bladder | 100% | 1315.24 | 21 / 21 | 100% | 15.47 | 503 / 504 |
| ovary | 100% | 1756.82 | 180 / 180 | 100% | 13.93 | 429 / 430 |
| thymus | 100% | 2048.45 | 653 / 653 | 100% | 14.33 | 603 / 605 |
| stomach | 100% | 1293.23 | 359 / 359 | 100% | 18.07 | 285 / 286 |
| prostate | 100% | 1683.14 | 245 / 245 | 100% | 15.50 | 500 / 502 |
| uterus | 100% | 1787.21 | 170 / 170 | 100% | 16.48 | 457 / 459 |
| pancreas | 100% | 1040.53 | 327 / 328 | 99% | 15.22 | 177 / 178 |
| brain | 99% | 974.66 | 2603 / 2642 | 100% | 11.10 | 705 / 705 |
| adrenal gland | 100% | 1276.77 | 258 / 258 | 97% | 10.98 | 223 / 230 |
| kidney | 100% | 1083.49 | 89 / 89 | 96% | 11.40 | 864 / 901 |
| skin | 100% | 1834.71 | 1809 / 1809 | 95% | 11.61 | 449 / 472 |
| liver | 100% | 846.28 | 226 / 226 | 87% | 6.95 | 354 / 406 |
| adipose | 100% | 1616.64 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 15.93 | 29 / 29 |
| spleen | 100% | 1910.35 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 15.55 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 8.44 | 1 / 1 |
| blood vessel | 100% | 1312.26 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 100% | 954.35 | 801 / 803 | 0% | 0 | 0 / 0 |
| heart | 98% | 1010.69 | 845 / 861 | 0% | 0 | 0 / 0 |
| peripheral blood | 88% | 990.71 | 819 / 929 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 74% | 5.51 | 59 / 80 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0006270 | Biological process | DNA replication initiation |
| GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
| GO_0000808 | Cellular component | origin recognition complex |
| GO_0000792 | Cellular component | heterochromatin |
| GO_0005664 | Cellular component | nuclear origin of replication recognition complex |
| GO_0005813 | Cellular component | centrosome |
| GO_0000781 | Cellular component | chromosome, telomeric region |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0016020 | Cellular component | membrane |
| GO_0000939 | Cellular component | inner kinetochore |
| GO_0005634 | Cellular component | nucleus |
| GO_0005515 | Molecular function | protein binding |
| GO_0003688 | Molecular function | DNA replication origin binding |
| Gene name | ORC2 |
| Protein name | Origin recognition complex subunit 2 |
| Synonyms | ORC2L |
| Description | FUNCTION: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K20me3 and H4K27me3. Stabilizes LRWD1, by protecting it from ubiquitin-mediated proteasomal degradation. Also stabilizes ORC3. . |
| Accessions | ENST00000234296.7 Q13416 C9JK08 ENST00000457595.1 ENST00000410039.5 B8ZZ80 |