RECQL4 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of RECQL4 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
uterus	100%	554.65	170 / 170	100%	38.38	458 / 459
bladder	100%	484.62	21 / 21	98%	31.65	492 / 504
esophagus	99%	971.52	1424 / 1445	99%	30.53	181 / 183
ovary	100%	523.99	180 / 180	97%	24.13	417 / 430
skin	99%	978.85	1796 / 1809	97%	24.45	460 / 472
intestine	100%	747.99	962 / 966	96%	30.68	504 / 527
stomach	94%	481.52	339 / 359	94%	29.75	270 / 286
prostate	99%	1738.36	243 / 245	88%	13.34	442 / 502
breast	94%	397.36	431 / 459	93%	21.38	1039 / 1118
lung	92%	437.39	529 / 578	90%	22.59	1037 / 1155
brain	95%	906.01	2519 / 2642	83%	12.11	586 / 705
thymus	100%	735.07	651 / 653	70%	8.89	423 / 605
pancreas	88%	283.10	287 / 328	80%	11.28	143 / 178
liver	77%	279.80	174 / 226	71%	12.22	288 / 406
adrenal gland	89%	302.27	230 / 258	51%	5.87	117 / 230
kidney	91%	424.42	81 / 89	31%	2.75	282 / 901
lymph node	0%	0	0 / 0	100%	46.56	29 / 29
spleen	100%	1116.34	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	40.18	45 / 45
ureter	0%	0	0 / 0	100%	50.52	1 / 1
blood vessel	89%	304.86	1193 / 1335	0%	0	0 / 0
adipose	87%	298.16	1043 / 1204	0%	0	0 / 0
eye	0%	0	0 / 0	75%	8.70	60 / 80
peripheral blood	64%	928.86	597 / 929	0%	0	0 / 0
heart	55%	139.77	477 / 861	0%	0	0 / 0
muscle	15%	32.56	120 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0032508	Biological process	DNA duplex unwinding
GO_0006281	Biological process	DNA repair
GO_0006268	Biological process	DNA unwinding involved in DNA replication
GO_0006260	Biological process	DNA replication
GO_0000724	Biological process	double-strand break repair via homologous recombination
GO_0000723	Biological process	telomere maintenance
GO_0061820	Biological process	telomeric D-loop disassembly
GO_0016020	Cellular component	membrane
GO_0005654	Cellular component	nucleoplasm
GO_0005737	Cellular component	cytoplasm
GO_0005694	Cellular component	chromosome
GO_0000781	Cellular component	chromosome, telomeric region
GO_0005634	Cellular component	nucleus
GO_0061821	Molecular function	telomeric D-loop binding
GO_0004386	Molecular function	helicase activity
GO_1990814	Molecular function	DNA/DNA annealing activity
GO_0009378	Molecular function	four-way junction helicase activity
GO_0000405	Molecular function	bubble DNA binding
GO_0046872	Molecular function	metal ion binding
GO_0005524	Molecular function	ATP binding
GO_0016853	Molecular function	isomerase activity
GO_0032357	Molecular function	oxidized purine DNA binding
GO_0005515	Molecular function	protein binding
GO_0016887	Molecular function	ATP hydrolysis activity
GO_0043138	Molecular function	3'-5' DNA helicase activity

Gene name	RECQL4
Protein name	RecQ protein-like 4 ATP-dependent DNA helicase Q4 (EC 5.6.2.4) (DNA 3'-5' helicase RecQ4) (DNA helicase, RecQ-like type 4) (RecQ4) (RTS) (RecQ protein-like 4) RecQ like helicase 4 DNA helicase (EC 3.6.4.12)
Synonyms	RECQ4
Description	FUNCTION: An ATP-dependent DNA helicase which unwinds dsDNA with a 3'-overhang in a 3'-5' direction . Does not unwind more than 18 bp of dsDNA . May modulate chromosome segregation. The N-terminal domain (residues 1-54) binds DNA Y-shaped DNA better than ss- or dsDNA . The core helicase domain binds ssDNA . .
Accessions	ENST00000524998.1 V9GY28 A0A087X072 ENST00000532846.2 ENST00000301323.7 ENST00000617875.6 V9GY60 V9GYB6 V9GYA3 ENST00000621189.4 ENST00000534538.1 V9GZ64 ENST00000531875.2 ENST00000534626.6 A0A087WTJ0 X2JEV0 O94761

RECQL4 report