GO_0000724 | OmnibusX

I. Literature review

Name	double-strand break repair via homologous recombination
ID	GO_0000724
collection_id	Biological process
Alternative ID	GO:0016924
Exact synonym	HDR, HRR, Rad51-dependent recombinational repair, Rhp51-dependent recombinational repair, homologous recombinational repair, homology-directed repair
Description	The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.
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Genes	POLN XRCC2 RAD51B ATM RAD51D RECQL AP5Z1 SMC6 PPP4C HUS1 MRE11 LIG3 WRN INIP REC8 MEIOB cx3_human RAD51AP1 shu_human RAD51C RPA1 mcm8-mcm9_human RPA2 WDR48 BLM RECQL5 NABP1 NABP2 inip-ints3-nabp1_human ZMYND8 smc5-smc6_human POGZ RAD54B H2AX brca2-palb2_human FEN1 UHRF1 MCM8 inip-ints3-nabp2_human NBN SWSAP1 SLF2 ERCC4 AUNIP swi5-sfr1_human RFWD3 RPA3 MMS22L HUS1B KASH5 PSMD14 HTATSF1 BRCA1 PALB2 smc5-smc6_human-1 btr_human ANKLE1 slx1-slx4_human FBH1 TOP3A YY1 RMI1 SPIDR NUCKS1 INTS3 RBBP8 EPC1 TOPBP1 NSMCE1 SLX1A RNF138 HELQ MCM9 RPA4 FAN1 AP5S1 EID3 ERCC5 KAT5 RECQL4 ZSWIM7 SAMHD1 EXD2 KDM4D UBE2N rpa_human RMI2 GEN1 SWI5 SFPQ POLL SEM1 RAD50 REV3L NSMCE2 CHD4 SMC5 SLX4 RAD52 NSMCE3 MBTD1 RNF169 RAD51 BRCA2 INO80 XRCC3 TONSL MORF4L1 SFR1 SLF1 NSMCE4A ZFYVE26

double-strand break repair via homologous recombination

I. Literature review