AP5S1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of AP5S1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of AP5S1 at tissue level.

III. Associated gene sets

GO_0000724Biological processdouble-strand break repair via homologous recombination
GO_0015031Biological processprotein transport
GO_0016192Biological processvesicle-mediated transport
GO_0016197Biological processendosomal transport
GO_0030119Cellular componentAP-type membrane coat adaptor complex
GO_0005764Cellular componentlysosome
GO_0031902Cellular componentlate endosome membrane
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0044599Cellular componentAP-5 adaptor complex
GO_0005765Cellular componentlysosomal membrane
GO_0005770Cellular componentlate endosome
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameAP5S1
Protein nameAP-5 complex subunit sigma-1 (Adaptor-related protein complex 5 sigma subunit) (Sigma5)
Adaptor related protein complex 5 subunit sigma 1
SynonymsC20orf29
DescriptionFUNCTION: As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport. According to PubMed:20613862, it is required for efficient homologous recombination DNA double-strand break repair. .

AccessionsENST00000246041.6
ENST00000379567.6
ENST00000615891.2
A2A2L4
Q9NUS5
ENST00000455742.5
Q5JX74
ENST00000379573.6