SFR1 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of SFR1 at tissue level.

III. Associated gene sets

GO_0000724Biological processdouble-strand break repair via homologous recombination
GO_0071391Biological processcellular response to estrogen stimulus
GO_0045893Biological processpositive regulation of DNA-templated transcription
GO_0005813Cellular componentcentrosome
GO_0005730Cellular componentnucleolus
GO_0005654Cellular componentnucleoplasm
GO_0032798Cellular componentSwi5-Sfr1 complex
GO_0005634Cellular componentnucleus
GO_0030374Molecular functionnuclear receptor coactivator activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSFR1
Protein nameSwi5-dependent recombination DNA repair protein 1 homolog (Meiosis protein 5 homolog)
SynonymsMEIR5
MEI5
C10orf78
DescriptionFUNCTION: Component of the SWI5-SFR1 complex, a complex required for double-strand break repair via homologous recombination . Acts as a transcriptional modulator for ESR1 . .

AccessionsQ86XK3
ENST00000369729.7 [Q86XK3-3]
ENST00000369727.4 [Q86XK3-1]