Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 14 studies | 28% ± 10% | |
adipocyte | 9 studies | 24% ± 8% | |
fibroblast | 9 studies | 23% ± 6% | |
astrocyte | 9 studies | 29% ± 12% | |
oligodendrocyte | 8 studies | 28% ± 8% | |
microglial cell | 7 studies | 26% ± 8% | |
glutamatergic neuron | 6 studies | 47% ± 25% | |
macrophage | 6 studies | 31% ± 6% | |
epithelial cell | 6 studies | 30% ± 15% | |
type II pneumocyte | 6 studies | 27% ± 8% | |
GABAergic neuron | 6 studies | 40% ± 19% | |
B cell | 5 studies | 22% ± 3% | |
interneuron | 5 studies | 38% ± 22% | |
myeloid cell | 5 studies | 24% ± 7% | |
endothelial cell of lymphatic vessel | 5 studies | 26% ± 6% | |
club cell | 5 studies | 22% ± 7% | |
smooth muscle cell | 5 studies | 21% ± 3% | |
type I pneumocyte | 5 studies | 25% ± 7% | |
natural killer cell | 4 studies | 16% ± 1% | |
neuron | 4 studies | 28% ± 13% | |
cardiac muscle cell | 4 studies | 24% ± 1% | |
dendritic cell | 4 studies | 21% ± 7% | |
ciliated cell | 4 studies | 20% ± 5% | |
lymphocyte | 4 studies | 22% ± 5% | |
oligodendrocyte precursor cell | 4 studies | 34% ± 10% | |
monocyte | 4 studies | 25% ± 6% | |
pericyte | 4 studies | 25% ± 7% | |
mesothelial cell | 3 studies | 24% ± 5% | |
hepatocyte | 3 studies | 38% ± 23% | |
T cell | 3 studies | 18% ± 3% | |
alveolar macrophage | 3 studies | 28% ± 8% | |
basal cell | 3 studies | 31% ± 17% | |
transit amplifying cell | 3 studies | 32% ± 21% | |
granule cell | 3 studies | 22% ± 5% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
bladder | 100% | 3058.14 | 21 / 21 | 100% | 16.81 | 504 / 504 |
esophagus | 100% | 2755.98 | 1445 / 1445 | 100% | 26.53 | 183 / 183 |
intestine | 100% | 2955.74 | 966 / 966 | 100% | 19.74 | 527 / 527 |
prostate | 100% | 2853.69 | 245 / 245 | 100% | 18.33 | 502 / 502 |
stomach | 100% | 2108.72 | 359 / 359 | 100% | 19.97 | 286 / 286 |
breast | 100% | 3000.63 | 459 / 459 | 100% | 22.08 | 1117 / 1118 |
lung | 100% | 2938.79 | 578 / 578 | 100% | 18.71 | 1152 / 1155 |
uterus | 100% | 3091.53 | 170 / 170 | 100% | 18.65 | 457 / 459 |
thymus | 100% | 2976.50 | 653 / 653 | 100% | 19.76 | 602 / 605 |
kidney | 100% | 2095.07 | 89 / 89 | 99% | 16.49 | 895 / 901 |
pancreas | 100% | 1314.57 | 327 / 328 | 99% | 17.71 | 177 / 178 |
ovary | 100% | 2925.33 | 180 / 180 | 99% | 12.31 | 426 / 430 |
brain | 99% | 1768.31 | 2624 / 2642 | 100% | 19.05 | 703 / 705 |
skin | 100% | 3426.75 | 1809 / 1809 | 99% | 20.12 | 466 / 472 |
liver | 100% | 1373.21 | 226 / 226 | 96% | 10.08 | 390 / 406 |
adrenal gland | 100% | 2083.00 | 258 / 258 | 96% | 10.81 | 220 / 230 |
adipose | 100% | 3000.99 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 2740.04 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 16.29 | 29 / 29 |
muscle | 100% | 2974.78 | 803 / 803 | 0% | 0 | 0 / 0 |
spleen | 100% | 2962.58 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 21.26 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 9.67 | 1 / 1 |
heart | 98% | 1468.31 | 845 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 98% | 15.10 | 78 / 80 |
peripheral blood | 87% | 1401.10 | 811 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0006281 | Biological process | DNA repair |
GO_0045995 | Biological process | regulation of embryonic development |
GO_0030307 | Biological process | positive regulation of cell growth |
GO_0034644 | Biological process | cellular response to UV |
GO_0000070 | Biological process | mitotic sister chromatid segregation |
GO_0045739 | Biological process | positive regulation of DNA repair |
GO_0006302 | Biological process | double-strand break repair |
GO_0070914 | Biological process | UV-damage excision repair |
GO_0006282 | Biological process | regulation of DNA repair |
GO_2000045 | Biological process | regulation of G1/S transition of mitotic cell cycle |
GO_0060382 | Biological process | regulation of DNA strand elongation |
GO_1904507 | Biological process | positive regulation of telomere maintenance in response to DNA damage |
GO_0051301 | Biological process | cell division |
GO_0006338 | Biological process | chromatin remodeling |
GO_0000724 | Biological process | double-strand break repair via homologous recombination |
GO_0006351 | Biological process | DNA-templated transcription |
GO_0010571 | Biological process | positive regulation of nuclear cell cycle DNA replication |
GO_0045893 | Biological process | positive regulation of DNA-templated transcription |
GO_0051225 | Biological process | spindle assembly |
GO_0000723 | Biological process | telomere maintenance |
GO_0033044 | Biological process | regulation of chromosome organization |
GO_0071479 | Biological process | cellular response to ionizing radiation |
GO_0006275 | Biological process | regulation of DNA replication |
GO_0051726 | Biological process | regulation of cell cycle |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0005874 | Cellular component | microtubule |
GO_0005654 | Cellular component | nucleoplasm |
GO_0016604 | Cellular component | nuclear body |
GO_0005829 | Cellular component | cytosol |
GO_0031011 | Cellular component | Ino80 complex |
GO_0005819 | Cellular component | spindle |
GO_0005634 | Cellular component | nucleus |
GO_0003677 | Molecular function | DNA binding |
GO_0042393 | Molecular function | histone binding |
GO_0043014 | Molecular function | alpha-tubulin binding |
GO_0005524 | Molecular function | ATP binding |
GO_0140658 | Molecular function | ATP-dependent chromatin remodeler activity |
GO_0008094 | Molecular function | ATP-dependent activity, acting on DNA |
GO_0005515 | Molecular function | protein binding |
GO_0003779 | Molecular function | actin binding |
GO_0016887 | Molecular function | ATP hydrolysis activity |
Gene name | INO80 |
Protein name | Chromatin-remodeling ATPase INO80 (hINO80) (EC 3.6.4.-) (DNA helicase-related INO80 complex homolog 1) (DNA helicase-related protein INO80) (INO80 complex subunit A) INO80 complex ATPase subunit Chromatin-remodeling ATPase INO80 (EC 3.6.4.-) |
Synonyms | INOC1 KIAA1259 INO80A |
Description | FUNCTION: ATPase component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and DNA repair . Binds DNA . As part of the INO80 complex, remodels chromatin by shifting nucleosomes . Regulates transcription upon recruitment by YY1 to YY1-activated genes, where it acts as an essential coactivator . Involved in UV-damage excision DNA repair . The contribution to DNA double-strand break repair appears to be largely indirect through transcriptional regulation . Involved in DNA replication . Required for microtubule assembly during mitosis thereby regulating chromosome segregation cycle . . FUNCTION: ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair. . FUNCTION: ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair. . FUNCTION: ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair. . |
Accessions | H0YNL3 ENST00000557849.1 ENST00000559995.2 ENST00000648947.1 H0YKH3 ENST00000696949.1 ENST00000558357.6 Q9ULG1 A0A8V8TLQ3 H0YMN5 |