I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| epithelial cell | 3 studies | 20% ± 3% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| epithelial cell | 3 studies | 20% ± 3% |
Insufficient scRNA-seq data for expression of AP5Z1 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 100% | 2429.02 | 1445 / 1445 | 100% | 17.46 | 183 / 183 |
| pancreas | 100% | 1460.04 | 328 / 328 | 100% | 17.85 | 178 / 178 |
| uterus | 100% | 2663.06 | 170 / 170 | 100% | 18.16 | 459 / 459 |
| thymus | 100% | 2885.17 | 653 / 653 | 100% | 14.98 | 603 / 605 |
| intestine | 100% | 2912.60 | 966 / 966 | 100% | 20.18 | 525 / 527 |
| adrenal gland | 100% | 3955.48 | 258 / 258 | 100% | 19.36 | 229 / 230 |
| liver | 100% | 1364.21 | 226 / 226 | 100% | 13.63 | 404 / 406 |
| kidney | 100% | 2380.07 | 89 / 89 | 99% | 14.01 | 896 / 901 |
| prostate | 100% | 2980.64 | 245 / 245 | 99% | 16.62 | 499 / 502 |
| skin | 100% | 4093.65 | 1809 / 1809 | 99% | 30.86 | 469 / 472 |
| stomach | 100% | 2219.92 | 359 / 359 | 99% | 19.48 | 284 / 286 |
| breast | 100% | 2691.18 | 459 / 459 | 99% | 14.98 | 1109 / 1118 |
| lung | 100% | 2996.09 | 577 / 578 | 99% | 17.85 | 1146 / 1155 |
| ovary | 100% | 2476.31 | 180 / 180 | 99% | 12.84 | 425 / 430 |
| bladder | 100% | 2835.38 | 21 / 21 | 99% | 20.49 | 498 / 504 |
| brain | 99% | 1636.57 | 2610 / 2642 | 100% | 20.18 | 705 / 705 |
| adipose | 100% | 2847.50 | 1204 / 1204 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 100% | 28.68 | 80 / 80 |
| lymph node | 0% | 0 | 0 / 0 | 100% | 33.48 | 29 / 29 |
| spleen | 100% | 5370.17 | 241 / 241 | 0% | 0 | 0 / 0 |
| tonsil | 0% | 0 | 0 / 0 | 100% | 15.59 | 45 / 45 |
| ureter | 0% | 0 | 0 / 0 | 100% | 10.63 | 1 / 1 |
| blood vessel | 100% | 2397.21 | 1334 / 1335 | 0% | 0 | 0 / 0 |
| peripheral blood | 99% | 3392.52 | 922 / 929 | 0% | 0 | 0 / 0 |
| heart | 98% | 1175.45 | 842 / 861 | 0% | 0 | 0 / 0 |
| muscle | 91% | 930.22 | 734 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| GO_0000724 | Biological process | double-strand break repair via homologous recombination |
| GO_0015031 | Biological process | protein transport |
| GO_0016192 | Biological process | vesicle-mediated transport |
| GO_0016197 | Biological process | endosomal transport |
| GO_0016607 | Cellular component | nuclear speck |
| GO_0030119 | Cellular component | AP-type membrane coat adaptor complex |
| GO_0005654 | Cellular component | nucleoplasm |
| GO_0044599 | Cellular component | AP-5 adaptor complex |
| GO_0005770 | Cellular component | late endosome |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| GO_0005515 | Molecular function | protein binding |
| Gene name | AP5Z1 |
| Protein name | Adaptor related protein complex 5 subunit zeta 1 AP-5 complex subunit zeta-1 (Adaptor-related protein complex 5 zeta subunit) (Zeta5) |
| Synonyms | SPG48 KIAA0415 |
| Description | FUNCTION: As part of AP-5, a probable fifth adaptor protein complex it may be involved in endosomal transport. According to PubMed:20613862 it is a putative helicase required for efficient homologous recombination DNA double-strand break repair. . |
| Accessions | A0A3B3ISN8 ENST00000650310.1 A0A3B3IU94 ENST00000649063.2 [O43299-1] ENST00000649315.1 A0A3B3ITJ1 ENST00000648360.1 ENST00000650451.1 O43299 A0A3B3ISJ0 A0A3B3IRY4 ENST00000650581.1 ENST00000647984.1 A0A3B3IS81 ENST00000648237.1 ENST00000648925.1 [O43299-2] A0A3B3IRY2 |
