SPIDR report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0000724Biological processdouble-strand break repair via homologous recombination
GO_0010569Biological processregulation of double-strand break repair via homologous recombination
GO_0006974Biological processDNA damage response
GO_0072711Biological processcellular response to hydroxyurea
GO_0070202Biological processregulation of establishment of protein localization to chromosome
GO_0071479Biological processcellular response to ionizing radiation
GO_0072757Biological processcellular response to camptothecin
GO_2000781Biological processpositive regulation of double-strand break repair
GO_0031334Biological processpositive regulation of protein-containing complex assembly
GO_0005654Cellular componentnucleoplasm
GO_0000228Cellular componentnuclear chromosome
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameSPIDR
Protein nameDNA repair-scaffolding protein (Scaffolding protein involved in DNA repair)
Scaffold protein involved in DNA repair (cDNA FLJ31118 fis, clone IMR322000656)
Scaffold protein involved in DNA repair
Scaffold protein involved in DNA repair (cDNA FLJ59936)
SynonymsKIAA0146
DescriptionFUNCTION: Plays a role in DNA double-strand break (DBS) repair via homologous recombination (HR). Serves as a scaffolding protein that helps to promote the recruitment of DNA-processing enzymes like the helicase BLM and recombinase RAD51 to site of DNA damage, and hence contributes to maintain genomic integrity. .

AccessionsQ14159
ENST00000519661.5
E5RJJ2
E5RFY2
E5RIU7
ENST00000523814.5
ENST00000522117.5
ENST00000517693.5
ENST00000518074.5 [Q14159-3]
B4DMX9
ENST00000518060.5
ENST00000524126.5
B3KP42
ENST00000517619.5
E5RGX8
ENST00000522222.5
H0YBC9
ENST00000297423.9 [Q14159-1]
E5RIB8
E5RGV8
ENST00000517824.5
ENST00000524006.5
ENST00000541342.2 [Q14159-2]
E7EVI9
ENST00000519401.5
ENST00000524033.5
E5RHG3