Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 24 studies | 45% ± 16% | |
astrocyte | 18 studies | 40% ± 18% | |
microglial cell | 15 studies | 52% ± 15% | |
fibroblast | 14 studies | 45% ± 16% | |
macrophage | 13 studies | 51% ± 22% | |
oligodendrocyte precursor cell | 13 studies | 48% ± 17% | |
smooth muscle cell | 11 studies | 36% ± 14% | |
glutamatergic neuron | 11 studies | 62% ± 25% | |
oligodendrocyte | 11 studies | 34% ± 13% | |
GABAergic neuron | 10 studies | 54% ± 24% | |
pericyte | 10 studies | 41% ± 13% | |
myeloid cell | 9 studies | 46% ± 23% | |
adipocyte | 9 studies | 49% ± 14% | |
mast cell | 9 studies | 35% ± 13% | |
ciliated cell | 9 studies | 38% ± 21% | |
endothelial cell of lymphatic vessel | 9 studies | 46% ± 18% | |
epithelial cell | 8 studies | 42% ± 20% | |
dendritic cell | 8 studies | 40% ± 16% | |
B cell | 7 studies | 38% ± 11% | |
mesothelial cell | 7 studies | 46% ± 14% | |
basal cell | 7 studies | 51% ± 25% | |
neuron | 6 studies | 45% ± 26% | |
interneuron | 6 studies | 62% ± 24% | |
T cell | 6 studies | 37% ± 12% | |
type II pneumocyte | 6 studies | 58% ± 21% | |
club cell | 6 studies | 51% ± 22% | |
cardiac muscle cell | 5 studies | 27% ± 6% | |
monocyte | 5 studies | 67% ± 11% | |
type I pneumocyte | 5 studies | 53% ± 9% | |
granule cell | 4 studies | 55% ± 15% | |
CD4-positive, alpha-beta T cell | 4 studies | 30% ± 9% | |
vein endothelial cell | 4 studies | 38% ± 21% | |
Mueller cell | 4 studies | 47% ± 15% | |
amacrine cell | 4 studies | 36% ± 14% | |
retina horizontal cell | 4 studies | 39% ± 8% | |
retinal cone cell | 4 studies | 45% ± 12% | |
retinal ganglion cell | 4 studies | 45% ± 17% | |
retinal rod cell | 4 studies | 38% ± 8% | |
respiratory goblet cell | 4 studies | 60% ± 22% | |
natural killer cell | 4 studies | 37% ± 8% | |
leukocyte | 4 studies | 55% ± 11% | |
hepatic stellate cell | 3 studies | 42% ± 20% | |
classical monocyte | 3 studies | 20% ± 4% | |
GABAergic interneuron | 3 studies | 55% ± 4% | |
progenitor cell | 3 studies | 38% ± 12% | |
plasma cell | 3 studies | 29% ± 10% | |
CD8-positive, alpha-beta T cell | 3 studies | 28% ± 7% | |
endothelial cell of artery | 3 studies | 27% ± 10% | |
mononuclear phagocyte | 3 studies | 45% ± 21% | |
GABAergic amacrine cell | 3 studies | 29% ± 13% | |
OFF-bipolar cell | 3 studies | 32% ± 9% | |
ON-bipolar cell | 3 studies | 34% ± 13% | |
glycinergic amacrine cell | 3 studies | 40% ± 8% | |
endothelial cell of vascular tree | 3 studies | 52% ± 14% | |
hepatocyte | 3 studies | 61% ± 19% | |
retinal pigment epithelial cell | 3 studies | 48% ± 27% | |
abnormal cell | 3 studies | 38% ± 23% | |
connective tissue cell | 3 studies | 37% ± 16% | |
alveolar macrophage | 3 studies | 74% ± 9% | |
capillary endothelial cell | 3 studies | 35% ± 6% | |
lymphocyte | 3 studies | 43% ± 9% | |
muscle cell | 3 studies | 31% ± 9% | |
goblet cell | 3 studies | 44% ± 32% | |
transit amplifying cell | 3 studies | 46% ± 36% | |
mucus secreting cell | 3 studies | 55% ± 4% | |
regulatory T cell | 3 studies | 32% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 100% | 4339.47 | 578 / 578 | 100% | 35.23 | 1155 / 1155 |
ovary | 100% | 4763.42 | 180 / 180 | 100% | 24.98 | 430 / 430 |
esophagus | 100% | 2791.34 | 1444 / 1445 | 100% | 27.56 | 183 / 183 |
breast | 100% | 4071.61 | 459 / 459 | 100% | 36.19 | 1116 / 1118 |
stomach | 100% | 2851.52 | 359 / 359 | 100% | 22.19 | 285 / 286 |
intestine | 100% | 3031.84 | 966 / 966 | 100% | 21.89 | 525 / 527 |
bladder | 100% | 3412.95 | 21 / 21 | 100% | 28.14 | 502 / 504 |
prostate | 100% | 4041.64 | 245 / 245 | 100% | 34.72 | 500 / 502 |
thymus | 100% | 4330.85 | 653 / 653 | 99% | 30.25 | 601 / 605 |
pancreas | 100% | 2209.33 | 327 / 328 | 99% | 23.03 | 177 / 178 |
uterus | 100% | 3420.01 | 170 / 170 | 99% | 31.70 | 454 / 459 |
brain | 99% | 2453.17 | 2613 / 2642 | 100% | 21.88 | 705 / 705 |
kidney | 100% | 2496.89 | 89 / 89 | 97% | 19.63 | 870 / 901 |
liver | 100% | 1665.66 | 226 / 226 | 95% | 14.16 | 385 / 406 |
skin | 100% | 3301.65 | 1809 / 1809 | 95% | 18.66 | 447 / 472 |
adrenal gland | 100% | 2958.62 | 258 / 258 | 92% | 12.91 | 211 / 230 |
adipose | 100% | 3986.56 | 1204 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 3267.28 | 1335 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 12.71 | 29 / 29 |
spleen | 100% | 3916.05 | 241 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 100% | 6.35 | 1 / 1 |
tonsil | 0% | 0 | 0 / 0 | 98% | 29.04 | 44 / 45 |
heart | 97% | 1568.55 | 839 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 94% | 1799.53 | 873 / 929 | 0% | 0 | 0 / 0 |
muscle | 92% | 1904.14 | 741 / 803 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 84% | 15.97 | 67 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0000724 | Biological process | double-strand break repair via homologous recombination |
GO_0010569 | Biological process | regulation of double-strand break repair via homologous recombination |
GO_0006974 | Biological process | DNA damage response |
GO_0072711 | Biological process | cellular response to hydroxyurea |
GO_0070202 | Biological process | regulation of establishment of protein localization to chromosome |
GO_0071479 | Biological process | cellular response to ionizing radiation |
GO_0072757 | Biological process | cellular response to camptothecin |
GO_2000781 | Biological process | positive regulation of double-strand break repair |
GO_0031334 | Biological process | positive regulation of protein-containing complex assembly |
GO_0005654 | Cellular component | nucleoplasm |
GO_0000228 | Cellular component | nuclear chromosome |
GO_0005515 | Molecular function | protein binding |
Gene name | SPIDR |
Protein name | DNA repair-scaffolding protein (Scaffolding protein involved in DNA repair) Scaffold protein involved in DNA repair (cDNA FLJ31118 fis, clone IMR322000656) Scaffold protein involved in DNA repair Scaffold protein involved in DNA repair (cDNA FLJ59936) |
Synonyms | KIAA0146 |
Description | FUNCTION: Plays a role in DNA double-strand break (DBS) repair via homologous recombination (HR). Serves as a scaffolding protein that helps to promote the recruitment of DNA-processing enzymes like the helicase BLM and recombinase RAD51 to site of DNA damage, and hence contributes to maintain genomic integrity. . |
Accessions | Q14159 ENST00000519661.5 E5RJJ2 E5RFY2 E5RIU7 ENST00000523814.5 ENST00000522117.5 ENST00000517693.5 ENST00000518074.5 [Q14159-3] B4DMX9 ENST00000518060.5 ENST00000524126.5 B3KP42 ENST00000517619.5 E5RGX8 ENST00000522222.5 H0YBC9 ENST00000297423.9 [Q14159-1] E5RIB8 E5RGV8 ENST00000517824.5 ENST00000524006.5 ENST00000541342.2 [Q14159-2] E7EVI9 ENST00000519401.5 ENST00000524033.5 E5RHG3 |