REV3L report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0000724Biological processdouble-strand break repair via homologous recombination
GO_0042276Biological processerror-prone translesion synthesis
GO_0006261Biological processDNA-templated DNA replication
GO_0005730Cellular componentnucleolus
GO_0005654Cellular componentnucleoplasm
GO_0016035Cellular componentzeta DNA polymerase complex
GO_0005634Cellular componentnucleus
GO_0003887Molecular functionDNA-directed DNA polymerase activity
GO_0003677Molecular functionDNA binding
GO_0005515Molecular functionprotein binding
GO_0051539Molecular function4 iron, 4 sulfur cluster binding
GO_0046872Molecular functionmetal ion binding
GO_0000166Molecular functionnucleotide binding

IV. Literature review

[source]
Gene nameREV3L
Protein nameREV3 like, DNA directed polymerase zeta catalytic subunit
REV3-like, catalytic subunit of DNA polymerase zeta (Yeast)
DNA polymerase zeta catalytic subunit (EC 2.7.7.7) (Protein reversionless 3-like) (REV3-like) (hREV3)
SynonymsPOLZ
REV3
DescriptionFUNCTION: Catalytic subunit of the DNA polymerase zeta complex, an error-prone polymerase specialized in translesion DNA synthesis (TLS). Lacks an intrinsic 3'-5' exonuclease activity and thus has no proofreading function. .

AccessionsC4TNX2
H0Y5T4
F2Z3A1
C4TNX0
C4TNX1
ENST00000368802.8 [O60673-1]
ENST00000413831.1
ENST00000435970.5 [O60673-2]
ENST00000434009.5
C4B7Q4
ENST00000358835.7 [O60673-1]
ENST00000422377.5
O60673