RECQL | OmnibusX

Name	Number of supported studies	Average coverage
natural killer cell	15 studies	20% ± 6%	Explore
endothelial cell	9 studies	22% ± 5%	Explore
CD8-positive, alpha-beta T cell	8 studies	19% ± 4%	Explore
CD16-positive, CD56-dim natural killer cell, human	6 studies	19% ± 2%	Explore
gamma-delta T cell	6 studies	20% ± 6%	Explore
endothelial cell of lymphatic vessel	5 studies	20% ± 4%	Explore
non-classical monocyte	5 studies	19% ± 6%	Explore
CD16-negative, CD56-bright natural killer cell, human	5 studies	19% ± 3%	Explore
mature NK T cell	5 studies	16% ± 1%	Explore
regulatory T cell	5 studies	19% ± 2%	Explore
macrophage	4 studies	19% ± 3%	Explore
effector CD8-positive, alpha-beta T cell	3 studies	21% ± 4%	Explore
naive B cell	3 studies	18% ± 2%	Explore
CD4-positive, alpha-beta T cell	3 studies	16% ± 1%	Explore
conventional dendritic cell	3 studies	25% ± 9%	Explore
effector memory CD8-positive, alpha-beta T cell	3 studies	19% ± 2%	Explore
epithelial cell	3 studies	21% ± 7%	Explore
fibroblast	3 studies	25% ± 9%	Explore
B cell	3 studies	18% ± 3%	Explore
GABAergic neuron	3 studies	21% ± 4%	Explore
glutamatergic neuron	3 studies	30% ± 2%	Explore
dendritic cell	3 studies	27% ± 5%	Explore
effector memory CD4-positive, alpha-beta T cell	3 studies	17% ± 2%	Explore
CD8-positive, alpha-beta memory T cell	3 studies	19% ± 4%	Explore
plasmacytoid dendritic cell	3 studies	22% ± 5%	Explore
double negative thymocyte	3 studies	20% ± 4%	Explore
memory B cell	3 studies	18% ± 2%	Explore

Name	Number of supported studies	Average coverage
peripheral blood	4 studies	18% ± 4%	Explore
brain	4 studies	22% ± 4%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	99%	1113.29	1431 / 1445	99%	22.45	181 / 183
lung	100%	1497.44	576 / 578	98%	23.46	1129 / 1155
breast	100%	1453.57	459 / 459	96%	25.99	1073 / 1118
intestine	100%	1123.10	965 / 966	95%	15.20	502 / 527
stomach	99%	742.62	354 / 359	97%	16.14	276 / 286
skin	100%	2067.04	1807 / 1809	92%	28.70	435 / 472
bladder	100%	1164.05	21 / 21	92%	16.22	462 / 504
kidney	99%	660.83	88 / 89	91%	21.11	822 / 901
uterus	100%	1241.90	170 / 170	90%	18.64	411 / 459
pancreas	95%	501.38	310 / 328	94%	17.32	168 / 178
thymus	100%	1110.84	652 / 653	88%	13.38	534 / 605
ovary	100%	870.24	180 / 180	82%	10.61	353 / 430
prostate	98%	726.31	240 / 245	83%	9.20	417 / 502
brain	84%	357.12	2211 / 2642	96%	16.52	675 / 705
adrenal gland	100%	1066.55	257 / 258	72%	8.65	166 / 230
liver	73%	355.88	165 / 226	65%	7.03	262 / 406
adipose	100%	1793.65	1204 / 1204	0%	0	0 / 0
blood vessel	100%	1863.28	1335 / 1335	0%	0	0 / 0
spleen	100%	1396.54	241 / 241	0%	0	0 / 0
muscle	99%	683.19	794 / 803	0%	0	0 / 0
heart	96%	839.16	825 / 861	0%	0	0 / 0
tonsil	0%	0	0 / 0	93%	26.87	42 / 45
lymph node	0%	0	0 / 0	83%	25.40	24 / 29
peripheral blood	81%	1349.97	749 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	43%	4.94	34 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0006281	Biological process	DNA repair
GO_0006268	Biological process	DNA unwinding involved in DNA replication
GO_0000724	Biological process	double-strand break repair via homologous recombination
GO_0031297	Biological process	replication fork processing
GO_0016020	Cellular component	membrane
GO_0005654	Cellular component	nucleoplasm
GO_0005737	Cellular component	cytoplasm
GO_0005694	Cellular component	chromosome
GO_0005634	Cellular component	nucleus
GO_1990814	Molecular function	DNA/DNA annealing activity
GO_0036121	Molecular function	double-stranded DNA helicase activity
GO_0009378	Molecular function	four-way junction helicase activity
GO_0003678	Molecular function	DNA helicase activity
GO_0046872	Molecular function	metal ion binding
GO_0005524	Molecular function	ATP binding
GO_0016853	Molecular function	isomerase activity
GO_0005515	Molecular function	protein binding
GO_0016887	Molecular function	ATP hydrolysis activity
GO_0043138	Molecular function	3'-5' DNA helicase activity

Gene name	RECQL
Protein name	ATP-dependent DNA helicase Q1 (EC 5.6.2.4) (DNA 3'-5' helicase Q1) (DNA helicase, RecQ-like type 1) (RecQ1) (DNA-dependent ATPase Q1) (RecQ protein-like 1) RecQ like helicase DNA helicase (EC 3.6.4.12)
Synonyms	RECQL1 RECQ1
Description	FUNCTION: DNA helicase that plays a role in DNA damage repair and genome stability . Exhibits a magnesium- and ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction . Full-length protein unwinds forked DNA substrates, resolves Holliday junctions, and has DNA strand annealing activity . Plays a role in restoring regressed replication forks . Required to restart stalled replication forks induced by abortive topoisomerase 1 and 2 lesions . May play a role in the repair of DNA that is damaged by ultraviolet light or other mutagens . .
Accessions	P46063 F5H4P4 F5H2L2 ENST00000444129.7 F8WD97 ENST00000539672.1 ENST00000536964.5 F8WA66 ENST00000542432.5 ENST00000536240.5 F5H3W0 ENST00000421138.6 F5GYB7 ENST00000314748.10 ENST00000396093.7

RECQL report