ANKLE1 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of ANKLE1 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ANKLE1 at tissue level.

III. Associated gene sets

GO_0000724Biological processdouble-strand break repair via homologous recombination
GO_0006974Biological processDNA damage response
GO_1905456Biological processregulation of lymphoid progenitor cell differentiation
GO_0090304Biological processnucleic acid metabolic process
GO_0006611Biological processprotein export from nucleus
GO_0045950Biological processnegative regulation of mitotic recombination
GO_1905453Biological processregulation of myeloid progenitor cell differentiation
GO_0000712Biological processresolution of meiotic recombination intermediates
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0004519Molecular functionendonuclease activity
GO_0004520Molecular functionDNA endonuclease activity

IV. Literature review

[source]
Gene nameANKLE1
Protein nameANKLE1 protein
Ankyrin repeat and LEM domain-containing protein 1 (EC 3.1.-.-) (Ankyrin repeat domain-containing protein 41) (LEM-domain containing protein 3)
Ankyrin repeat and LEM domain containing 1
SynonymsANKRD41
LEM3
DescriptionFUNCTION: Endonuclease that probably plays a role in the DNA damage response and DNA repair. .

AccessionsENST00000652132.1
ENST00000404085.7 [Q8NAG6-2]
ENST00000598347.2
A0JLW0
ENST00000394458.7
M0QX15
ENST00000594072.6
A0A0A0MSC6
M0R002
ENST00000404261.9
Q8NAG6
A0A499FJM0
A0A494C092