RMI2 | OmnibusX

Name	Number of supported studies	Average coverage
B cell	4 studies	26% ± 9%	Explore
epithelial cell	3 studies	18% ± 3%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of RMI2 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
skin	100%	523.14	1803 / 1809	95%	14.48	450 / 472
ovary	93%	203.08	168 / 180	100%	18.90	428 / 430
lung	78%	125.98	453 / 578	96%	19.44	1114 / 1155
bladder	76%	135.38	16 / 21	98%	24.63	496 / 504
intestine	75%	223.14	721 / 966	98%	19.85	514 / 527
stomach	67%	135.07	241 / 359	98%	17.51	280 / 286
esophagus	57%	242.45	821 / 1445	98%	17.52	180 / 183
uterus	55%	70.80	94 / 170	100%	45.09	458 / 459
thymus	64%	77.96	418 / 653	91%	14.46	548 / 605
kidney	89%	152.58	79 / 89	58%	4.86	526 / 901
breast	52%	58.85	238 / 459	95%	17.64	1062 / 1118
prostate	82%	121.46	201 / 245	46%	3.11	233 / 502
pancreas	40%	37.23	131 / 328	87%	10.54	154 / 178
adrenal gland	75%	84.56	193 / 258	30%	5.46	70 / 230
brain	62%	108.81	1640 / 2642	41%	4.03	286 / 705
lymph node	0%	0	0 / 0	100%	52.94	29 / 29
tonsil	0%	0	0 / 0	100%	45.30	45 / 45
ureter	0%	0	0 / 0	100%	23.70	1 / 1
spleen	100%	225.96	240 / 241	0%	0	0 / 0
liver	29%	47.00	66 / 226	50%	5.59	201 / 406
peripheral blood	69%	478.28	641 / 929	0%	0	0 / 0
eye	0%	0	0 / 0	49%	3.11	39 / 80
adipose	49%	50.90	584 / 1204	0%	0	0 / 0
blood vessel	22%	20.15	300 / 1335	0%	0	0 / 0
heart	22%	19.60	186 / 861	0%	0	0 / 0
muscle	17%	15.20	134 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0000724	Biological process	double-strand break repair via homologous recombination
GO_0006281	Biological process	DNA repair
GO_0043007	Biological process	maintenance of rDNA
GO_0071139	Biological process	resolution of DNA recombination intermediates
GO_0006260	Biological process	DNA replication
GO_2000042	Biological process	negative regulation of double-strand break repair via homologous recombination
GO_0033045	Biological process	regulation of sister chromatid segregation
GO_0016607	Cellular component	nuclear speck
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0031422	Cellular component	RecQ family helicase-topoisomerase III complex
GO_0005634	Cellular component	nucleus
GO_0003677	Molecular function	DNA binding
GO_0005515	Molecular function	protein binding

Gene name	RMI2
Protein name	RecQ mediated genome instability 2 RecQ-mediated genome instability protein 2 (hRMI2) (BLM-associated protein of 18 kDa) (BLAP18)
Synonyms	C16orf75
Description	FUNCTION: Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates. It is required to regulate sister chromatid segregation and to limit DNA crossover. Essential for the stability, localization, and function of BLM, TOP3A, and complexes containing BLM. In the RMI complex, it is required to target BLM to chromatin and stress-induced nuclear foci and mitotic phosphorylation of BLM. .
Accessions	ENST00000572173.1 [Q96E14-2] ENST00000312499.6 [Q96E14-1] I3L2E0 ENST00000576027.1 A0A3B3ISX4 Q96E14 ENST00000648619.1

RMI2 report